***************************************************************** 11/02/05 **** RADIATION BULLETIN(RADBULL) **** VOL 13.255 ***************************************************************** RADBULL IS PRODUCED BY THE ABALONE ALLIANCE CLEARINGHOUSE ***************************************************************** Send News Stories to news@energy-net.org with title on subject line and first line of body NUCLEAR POLICY 1 US: Las Vegas SUN: Carter: White House Manipulated Iraq Intel 2 Guardian Unlimited: Iran Sending Mixed Signals About Nukes 3 Guardian Unlimited: Iran Grants U.N. Access to Military Site 4 Korea: Digital Chosunilbo: U.S. Mulls Team to Discuss Korea Peace Tr 5 MSN-Mainichi Daily News: Korea says North stands to gain from implem 6 INSIDE JoongAng Daily: Chung lauds Seoul's role in warm cross-DMZ ti 7 MSN-Mainichi Daily News: Yokosuka says it doesn't want to host U.S. 8 Bellona: Adamov appeals extradition to US, Russian foreign ministry NUCLEAR REACTORS 9 US: NRC: Sunshine Act Meeting 10 US: APP.com: Views on reactor laid out for NRC | 11 US: JOURNAL NEWS: Indian Point inspections to increase 12 US: NRC: In the Matter of Entergy Operations, Inc., Grand Gulf Nucle 13 US: NRC: In the Matter of Entergy Operations, Inc., Grand Gulf Nucle 14 US: NRC: Notice of Public Scoping Meeting and Solicitation of Scopin 15 US: Hudson Valley News: NRC plans enhanced oversight of Indian Point 16 US: technicianonline.com: Reactor mystifies campus 17 Business Gazette: NUCLEAR SELL-OFF: EFFECTS ON SUPPLY CHAIN 18 Guardian Unlimited Bush: Venezuela Nuke Reactor Might Be OK NUCLEAR SECURITY 19 US: NRC: NRC Proposes $3,250 Civil Penalty for N.J. Firm over Loss o NUCLEAR SAFETY 20 [DU Information List] MoD concedes that gulf war syndrome does 21 [du-list] MoD concedes that gulf war syndrome does exist 22 [DU-WATCH] Beyond Treason: Veterans exposure- 23 Xinhua: S.Korean truck loaded with missile parts blasts near Daegu NUCLEAR FUEL CYCLE 24 US: Sydney Morning Herald: BHP plans uranium mine upgrade - 25 Sydney Morning Herald: NT nuclear waste dump jumps first hurdle - 26 Korea: Digital Chosunilbo: Locals Vote on Nuclear Waste Dump in Thei 27 INSIDE JoongAng Daily: [EDITORIALS] After the nuclear site vote 28 INSIDE JoongAng Daily: Nuclear waste ballot draws 60% turnout 29 INSIDE JoongAng Daily: [VIEWPOINT] Citizens asked to make a choice 30 US: Salt Lake Tribune: Dumping can be avoided 31 Xinhua: Ukraine denies burying nuclear waste near Russian border 32 Globe and Mail: Chiefs warn of nuclear waste plans for native territ 33 US: Review: Individuals respond to perchlorate differently 34 Nevada: Changes Being Planned For Yucca Mountain, 35 UK: News & Star: Irish demand action at Sellafield 36 US: Las Vegas SUN: BLM blocking Skull Valley nuclear waste project PEACE US DEPT. OF ENERGY 37 CH2M HILL Mound, Inc.: Announces Building Demolition Complete at ***************************************************************** ***************************************************************** FULL NEWS STORIES ***************************************************************** ***************************************************************** 1 Las Vegas SUN: Carter: White House Manipulated Iraq Intel Today: November 02, 2005 at 9:42:45 PST ASSOCIATED PRESS NEW YORK (AP) - The Bush Administration's prewar claims that Saddam Hussein had weapons of mass destruction were "manipulated, at least" to mislead the American people, former President Jimmy Carter said Wednesday. The decision to go to war was the culmination of a long-term plan to attack Iraq that resulted from the first President Bush not taking out Saddam, Carter said on NBC's "Today" show. Carter also said he supports the move by Senate Democrats to force an update on the investigation into prewar intelligence on Iraq, and says Republicans have been dragging their feet on the investigation. Democrats Tuesday used a rarely invoked Senate rule to force a secret session as a way to dramatize their assertions that the Bush administration misused intelligence in the run-up to the war in Iraq. A bipartisan committee has been appointed to review the investigation. All contents copyright 2005 Las Vegas SUN, Inc. ***************************************************************** 2 Guardian Unlimited: Iran Sending Mixed Signals About Nukes From the Associated Press [UP] Wednesday November 2, 2005 4:46 PM AP Photo VAH102 By GEORGE JAHN Associated Press Writer VIENNA, Austria (AP) - Iran is sending conflicting signals to an international community concerned about its nuclear agenda, granting U.N. inspectors access to a secret military site but also saying it would process a new batch of uranium that could be used to make atomic weapons, diplomats said Wednesday. The two developments showed that Iran was unwilling to meet international calls to give up enrichment and all linked activities even while casting itself as conciliatory and ready to cooperate with International Atomic Energy Agency inspectors probing its past nuclear activities. The last meeting of the 35-nation IAEA board told Iran in September to suspend all uranium enrichment-related activities, including conversion, and to give agency experts access to research, experts, locations and documents or face referral to the U.N. Security Council. Iran has stopped at conversion but insists it has the right to the next stage - enrichment. Uranium enrichment can produce either nuclear energy or the fissile core of weapons. The diplomats said IAEA experts were allowed to revisit the high-security military site in Parchin as they try to establish whether Tehran has a secret nuclear weapons program. Parchin has been linked by the United States and other nations to alleged experiments linked to nuclear arms. The IAEA had for months been trying to follow up on a visit in January for further checks of buildings and areas within the sprawling military complex as it looks for traces of radioactivity. That visit - which was closely controlled by authorities - revealed no such traces. But one of the diplomats - who like the others requested anonymity because he was not authorized to talk to the media about the sensitive investigation - said that over the past few days IAEA inspectors ``gained access to buildings'' previously out of bounds to them. The diplomat, who is close to the agency, said environmental swipes were taken from objects in the buildings and would be analyzed at IAEA laboratories. If those swipes reveal minute amounts of radioactivity, they would strengthen suspicions of nuclear-related work at Parchin. Because Parchin is run by the country's armed forces, such a discovery would weaken Iranian arguments that its nuclear programs are strictly nonmilitary. That, in turn, would strengthen sentiment that Tehran be referred to the Security Council for breaching the Nuclear Nonproliferation Treaty as early as Nov. 24, when the IAEA board of governors has scheduled its next meeting. The swipe results are expected before then. U.S. intelligence officials said last year that a specially secured site on the Parchin complex, about 20 miles southeast of Tehran, may be used in research on nuclear arms, specifically in making high-explosive components for use in such weapons. On Wednesday, British Prime Minister Tony Blair said military action against Iran was not being considered, but he said Tehran must change course. ``Nobody is talking about military threats or invasion of Iran or any of the rest of it,'' Blair told the House of Commons. He added that Iran's government ``has got to understand that the international community simply will not put up with their continued breach of the proper and normal standards of behavior that we expected from a member of the United Nations.'' The IAEA has not found any firm evidence to challenge Iranian assertions that its military is not involved in nuclear activities, but in a document last year expressed concern about reports ``relating to dual use equipment and materials which have applications ... in the nuclear military area.'' Diplomats said that phrasing alluded to Parchin. Before the next board meeting, IAEA inspectors also hope to be allowed to visit Lavizan-Shian, suspected of being the repository of equipment bought by its military that could be used in a nuclear weapons program The State Department last year said Lavizan-Shian's buildings had been dismantled and topsoil had been removed from the site in attempts to hide nuclear-weapons related experiments. Agency officials subsequently confirmed that the site had been razed, but Iran said work at the site, on the outskirts of Tehran, was part of construction unrelated to military or nuclear matters. Iran is under increasing pressure before the next IAEA board meeting to show it is cooperating with an agency probe of nearly 18 years of suspected clandestine nuclear activities as Tehran tries to derail a U.S.-backed European push to report it to the Security Council. Russia and China - council members who also sit on the IAEA board - oppose such a move. But Iranian President Mahmoud Ahmadinejad's calls last week for Israel to be ``wiped off the map'' have strengthened the U.S.-European hand. Russia was among the dozens of nations protesting his statements. ^--- On the Net: International Atomic Energy Agency: http://www.iaea.org Guardian Unlimited © Guardian Newspapers Limited 2005 ***************************************************************** 3 Guardian Unlimited: Iran Grants U.N. Access to Military Site From the Associated Press [UP] Wednesday November 2, 2005 12:31 PM By GEORGE JAHN Associated Press Writer VIENNA, Austria (AP) - Iran has granted U.N. nuclear inspectors new access to a high-security military site as part of efforts to avoid referral to the Security Council, diplomats said Wednesday. The diplomats said experts of the International Atomic Energy Agency were allowed to revisit Parchin as they try to establish whether Tehran has a secret nuclear weapons program. Parchin has been linked by the United States and other nations to alleged experiments linked to nuclear arms. The IAEA had for months been trying to follow up on a visit in January for further checks of buildings and areas within the sprawling military complex as it looks for traces of radioactivity. That visit - which was closely controlled by authorities - revealed no such traces. But one of the diplomats - who like the others requested anonymity because he was not authorized to talk to the media about the sensitive investigation - said that over the past few days IAEA inspectors ``gained access to buildings'' previously out of bounds to them. The diplomat, who is close to the agency, said environmental swipes were taken from objects in the buildings and would be analyzed at IAEA laboratories. If those swipes reveal minute amounts of radioactivity, they would strengthen suspicions of nuclear-related work at Parchin. Because Parchin is run by the country's armed forces, such a discovery would weaken Iranian arguments that its nuclear programs are strictly nonmilitary. That, in turn, would strengthen sentiment that Tehran be referred to the U.N. Security Council for breaching the Nuclear Nonproliferation Treaty as early as Nov. 24, when the IAEA's 35-nation board of governors has scheduled its next meeting. The swipe results are expected before then. U.S. intelligence officials said last year that a specially secured site on the Parchin complex, about 20 miles southeast of Tehran, may be used in research on nuclear arms, specifically in making high-explosive components for use in such weapons. On Wednesday, British Prime Minister Tony Blair said military action against Iran was not being considered, but he said Tehran must change course. ``Nobody is talking about military threats or invasion of Iran or any of the rest of it,'' Blair told the House of Commons. He added that Iran's government ``has got to understand that the international community simply will not put up with their continued breach of the proper and normal standards of behavior that we expected from a member of the United Nations.'' The IAEA has not found any firm evidence to challenge Iranian assertions that its military is not involved nuclear activities, but in a document last year has expressed concern about reports ``relating to dual use equipment and materials which have applications ... in the nuclear military area.'' Diplomats said that phrasing alluded to Parchin. Before the next board meeting, IAEA inspectors also hope to be allowed to visit Lavizan-Shian, suspected of being the repository of equipment bought by its military that could be used in a nuclear weapons program The State Department last year said Lavizan-Shian's buildings had been dismantled and topsoil had been removed from the site in attempts to hide nuclear-weapons related experiments. Agency officials subsequently confirmed that the site had been razed, but Iran said work at the site, on the outskirts of Tehran, was part of construction unrelated to military or nuclear matters. Iran is under increasing pressure before the next IAEA board meeting to show it is cooperating with a more than three-year IAEA probe of nearly 18 years of suspected clandestine nuclear activities as it tries to derail a U.S.-backed European push to report it to the Security Council. Russia and China - council members who also sit on the IAEA board - are opposed to such a move. But calls last week by Iranian President Mahmoud Ahmadinejad called for Israel to be ``wiped off the map,'' have strengthened the U.S.-European hand by focusing on concerns over Iran's nuclear ambitions. Russia was among the dozens of nations protesting his statements. --- On the Net: www.iaea.org Guardian Unlimited © Guardian Newspapers Limited 2005 ***************************************************************** 4 Korea: Digital Chosunilbo: U.S. Mulls Team to Discuss Korea Peace Treaty Home> National/Politics Updated Nov.2,2005 21:46 KST The U.S. government could form a working-level team that would discuss a permanent peace treaty with North Korea to replace the armistice that halted the Korean War, Japan¡¯s Yomiuri Shimbun reported. The paper quoted a high-ranking U.S. official as saying Washington had drawn up a blueprint for the next round of six-party talks on North Korea¡¯s nuclear program that identifies three areas of discussion: the nuclear program, a peace mechanism, and economic support. The paper said the peace treaty would be dealt with at the working level. ¡°Despite adopting a joint statement in the last round of six-party talks where North Korea pledged to dismantle its nuclear program, no concrete steps have been taken to implement that agreement,¡± the paper said. The working-level talks were therefore aimed at clearing up the ambiguously worded parts. The Yomiuri said Washington wanted Tokyo, which was not a party to the Korean War, to become more actively involved in discussions on the peace framework, but Seoul strongly opposed this. (englishnews@chosun.com ) ***************************************************************** 5 MSN-Mainichi Daily News: Korea says North stands to gain from implementing nuclear agreement SEOUL -- North Korea's path to prosperity lies in implementing the promise it made at international disarmament talks to abandon its nuclear programs, South Korean Finance Minister Han Duck-soo said Wednesday. "We believe, and we presume, that there is a very high possibility for success because there is so much at stake on the part of North Korea to realize the contents of the six-party talks," Han told a gathering of foreign business associations and diplomats. Separately, South Korea's point man on North Korea said Wednesday the next round of talks should resume in about a week. "The six-way talks are supposed to be held around Nov. 9," Unification Minister Chung Dong-young said in a speech, adding that consultations are under way among the participants on how to advance the talks. His remarks came a day after Japanese media reported that China had proposed starting the next round on Nov. 9 in Beijing. South Korean Foreign Minister Ban Ki-moon said host China would announce specific dates after consulting its dialogue partners, which along with the two Koreas include Japan, Russia and the United States. Ban expects a short session before a recess because the Asia-Pacific Economic Cooperation forum is scheduled for Nov. 18-19 in Busan, South Korea. China said Tuesday it was trying to get agreement for a start date within the next 10 days following President Hu Jintao's visit to North Korea, and the North Korean leader Kim Jong Il's promise to return to the talks. The six nations have been negotiating with North Korea to give up its nuclear ambitions since 2003. Those efforts achieved their first success in September when the North promised to abandon its nuclear programs in return for economic aid, security assurances and diplomatic recognition. But the communist country quickly imposed conditions, demanding a civilian nuclear reactor for power generation. Washington has rejected the demand. South Korea is drafting a roadmap on how to implement the agreement reached at the latest round of talks and conveyed its proposal to the United States, according to Chung. He didn't elaborate. Seoul has said it is ready to provide massive amounts of aid, including electricity, to the North if there is an agreement on its nuclear program. "Certainly we should incorporate North Korea into the international community" if it abides by the agreement, said Finance Minister Han. "That means some kind of market opening for North Korea is the only crucial way for us to ensure that North Korea will not be left behind and North Korea can make prosperity possible." Also Wednesday, the North denounced the United States for freezing U.S.-based assets of eight North Korean entities, describing the move as "pouring cold water" on its "sincere" efforts toward the next round of talks, the official Rodong Sinmun daily said in a Korean-language commentary carried by the Korean Central News Agency. The North also threatened unspecified countermeasures. Last month, Washington prohibited transactions between the companies and U.S. citizens and froze any assets they may have under U.S. jurisdiction. (AP) November 2, 2005 Copyright 2004-2005 THE MAINICHI NEWSPAPERS. All ***************************************************************** 6 INSIDE JoongAng Daily: Chung lauds Seoul's role in warm cross-DMZ ties November 3, 2005 KST November 03, 2005 ¤Ñ Unification Minister Chung Dong-young asserted yesterday that improved communications between North and South Korea was the basis of a recent international accord under which Pyongyang agreed to get rid of its nuclear weapons and programs, and reiterated the need for North-South reconciliation and cooperation. He was speaking at a forum organized by the JoongAng Ilbo and the Hyundai Research Institute. "I think the six-party talks in Beijing were the first opportunity to raise our voices on an issue concerning us, and it was the first time that the South and North communicated well," he said in his initial remarks. He repeated his desire for the Asia-Pacific Economic Cooperation forum to "reconfirm" the agreement reached by the six nations' negotiators in Beijing in September. The minister defended Seoul's generosity to North Korea, for example by food and fertilizer shipments and investments in the Kaesong Industrial Complex, against critics who contend that the generosity has not been reciprocated. He said that Seoul's support has led to increases in the number and the quality of cross-border exchanges. He said Seoul would continue providing such support. In another appearance yesterday, at the National Assembly's unification committee, Mr. Chung was a bit cryptic in discussing the spat between the Hyundai Group and North Korea over tours to the North. He said Hyundai still has an exclusive contract to conduct such tours, but said the Hyundai-North Korea business relations will not influence Seoul's decisions on doing business with North Korea. Pyongyang and Hyundai have been publicly fighting over the tour business in a spat triggered by the group's dismissal of its senior executive involved in that business. Mr. Chung is widely believed to be preparing to resign his portfolio in the next few months to return to a leadership role in the administration's Uri Party. by Ko Soo-suk, Jeong Yong-su africanu@joongang.co.kr> Copyright by Joins.com, Inc. ***************************************************************** 7 MSN-Mainichi Daily News: Yokosuka says it doesn't want to host U.S. nuclear-powered aircraft carrier Yokosuka Municipal Assembly voted unanimously Wednesday against plans to deploy a nuclear-powered aircraft carrier in the city, citing the feelings of people in a country where the U.S. dropped two atomic bombs. The 45-member assembly unanimously adopted a statement urging the central government to nullify the agreement with Washington to base a Nimitz-class nuclear aircraft carrier in the city starting in 2008, replacing an older conventional carrier, city spokesman Takahide Kurabayashi said. Yokosuka hosts the U.S. Seventh Fleet, the only U.S. fleet based overseas. American troops have been stationed in Japan since the end of World War II in 1945, but the Japanese public has long been wary of any U.S. nuclear presence because of opposition to nuclear weapons and a fear of radiation leaks. The decision to deploy the nuclear-powered carrier comes 60 years after the U.S. dropped atomic bombs on the Japanese cities of Hiroshima and Nagasaki in the closing days of the war. "Fully taking into account the feelings toward nuclear (issues) of local citizens and the Japanese people in the only country that suffered atomic bombings ... we request that the government nullify the deployment agreement, and that the U.S. government continue deploying a conventional aircraft carrier," the city assembly said. Kurabayashi said the statement would be sent to Japanese government officials, including Prime Minister Junichiro Koizumi. He said the city had no power to block the decision. Last week, the U.S. and Japanese governments announced plans for the U.S. Navy to station a nuclear-powered aircraft carrier in Japan for the first time. The U.S. Navy said it would have greater capabilities than the diesel-powered USS Kitty Hawk currently based at Yokosuka. On Saturday, about 80 people -- many of them victims of the U.S. atomic bombings -- rallied in Hiroshima against the plans to deploy the nuclear-powered carrier. "It makes me angry that America can even consider basing a nuclear carrier in Japan, the only country in the world to have suffered a nuclear attack," said Kazutoshi Kajikawa, who heads the Hiroshima Peace Movement Center. (AP) November 2, 2005 Copyright 2004-2005 THE MAINICHI NEWSPAPERS. All ***************************************************************** 8 Bellona: Adamov appeals extradition to US, Russian foreign ministry to intervene Russia says a Swiss court's ruling that allowed ex-Atomic Energy Minister Yevgeny Adamov's extradition to the United States affects Russia's rights and interests and intends to intervene in the proceedings as one of the interested legal parties, the Ministry of Foreign affairs said in a statement Tuesday, Interfax news agency reported. 2005-11-02 13:28 Lawyers for Adamovwho is charged with embezzling some $9m allocated by US government bodies to improve Russia’s nuclear securitymeanwhile filed an appeal with Switzerland’s highest court in Lausanne against the extradition. The Swiss Federal Justice Department announced its decision to extradite the former Russian minister on October 3. "Russia has repeatedly expressed its disagreement with the Swiss authorities' decision on Adamov's extradition to the [United States], which, in its opinion, is not based on an objective assessment of all circumstances of the case and does not comply with the provisions of international law that were applied," the Russia foreign ministry said. "Taking into account that the decision of the Swiss authorities directly affects the Russian Federation's rights and legitimate interests, it intends to take part in the proceedings, as well." Until the Lausanne court hands down a decision on the appeal, Adamov will remain in custody in Bern, where he was arrested May 3rd on a US Warrant. The Lausanne court is not bound by a deadline, and its verdicts are not subject to appeal. If convicted by an American court, Adamov may face a prison sentence of up to 60 years and a $1.75 million fine. The Russian Prosecutor General's Office also launched proceedings against Adamov, charging him with embezzlement and abuse of office. Both countries petitioned the Swiss judiciary for Adamov's extradition. The official extradition request from the U.S. was received June 24 and the request from Russia, May 17th. Publisher: , President: Information: , Technical contact: Telephone: +47 23 23 46 00 Telefax: +47 22 38 38 62 * P.O.Box 2141 Grunerlokka, 0505 Oslo, Norway ***************************************************************** 9 NRC: Sunshine Act Meeting FR Doc 05-21915 [Federal Register: November 2, 2005 (Volume 70, Number 211)] [Notices] [Page 66473-66474] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr02no05-139] Date: Weeks of October 31, November 7, 14, 21, 28, December 5, 2005. Place: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland. Status: Public and Closed. Matters to be Considered Week of October 31, 2005 Tuesday, November 1, 2005. 9:30 a.m.--Briefing on Implementation of Davis-Besse Lessons Learned Task Force (DBLLTF) Recommendations (Public Meeting) (Contact: Brendan Moroney, 301-415-3974). This meeting will be webcast live at the Web address: http://www.nrc.gov . Week of November 7, 2005--Tentative There are no meetings scheduled for the Week of November 7, 2005. Week of November 14, 2005--Tentative There are no meetings scheduled for the Week of November 14, 2005. Week of November 21, 2005--Tentative Monday, November 21, 2005. 9:30 a.m.--Briefing on Status of New Reactor Issues, Part 1 (Public Meeting) (Contact: Laura Dudes, 301-415-0146). 1:30 p.m.--Briefing on Status of New Reactor Issues, Part 2 (Public Meeting) (Contact Laura Dudes, 301-415-0146). These meetings will be webcast live at the Web address: http://www.nrc.gov . Week of November 28, 2005--Tentative Tuesday, November 29, 2005. 9:30 a.m.--Discussion of Management Issues (Closed-Ex. 2). Wednesday, November 30, 2005. 9:30 a.m.--Briefing on EEO Program (Public Meeting) (Contact: Corenthis Kelley, 301-415-7380. This meeting will be webcast live at the Web address: http://www.nrc.gov . Week of December 5, 2005--Tentative Thursday, December 8, 2005. 1 p.m.--Meeting with the Advisory Committee on Reactor Safeguards (ACRS) (Contact: John Larkins, 301-415-7360). This meeting will be webcast live at the Web address: http://www.nrc.gov . *The schedule for Commission meetings is subject to change on short notice. To verify the status of meetings call (recording)--(301) 415- 1292. Contact person for more information Michelle Schroll, (301) 415- 1662. * * * * * The NRC Commission Meeting Schedule can be found on the Internet at: http://www.nrc.gov/what-we-do/policy-making/schedule.html. * * * * * The NRC provides reasonable accommodation to individuals with disabilities where appropriate. If you need a reasonable accommodation to participaate in these public meetings, or need this meeting notice or the transcript or other information from the public meetings in another format (e.g. braille, large print), please notify the NRC's Disability Program Coordinator, August Spector, at 301-415-7080, TDD: 301-4152100, or by e-mail at aks@nrc.gov. Determinations on requests for reasonable accommodation will be made on case-by-case basis. * * * * * This notice is distributed by mail to several hundred subscribers; if you no longer wish to receive it, or would like to be added to the distribution, please contact the Office of the Secretary, Washington, DC 20555 (301-415-1969). In addition, distribution of this meeting notice nover the Internet system is available. If you are interested in receiving this Commission meeting schedule electronically, please send an electronic message to dkw@nrc.gov. [[Page 66474]] Dated: October 27, 2005. R. Michelle Schroll, Office of the Secretary. [FR Doc. 05-21915 Filed 10-31-05; 9:59 am] BILLING CODE 7590-01-M ***************************************************************** 10 APP.com: Views on reactor laid out for NRC | Asbury Park Press Online Wednesday, November 2, 2005 Oyster Creek's impact is topic BY TODD B. BATES AND BRIAN PRINCE STAFF WRITERS TOMS RIVER — Oyster Creek has minimal impact on the environment. Or it has an enormous impact. Speakers voiced those views, and many in between, on the nuclear power plant's environmental record at two U.S. Nuclear Regulatory Commission public meetings Tuesday. The meetings, which attracted dozens of citizens, activists, officials and others, centered on the NRC environmental review linked to the Lacey plant's request for a 20-year operating license extension beyond April 2009. "There's a tremendous environmental impact" when Oyster Creek continues to operate daily, said Donald Warren, a registered nurse who lives in Ship Bottom and is affiliated with Jersey Shore Nuclear Watch. Bud Swenson, site vice president at the AmerGen Energy Co. nuclear plant in Lacey, said that "today, Oyster Creek has the longest track record of safe operations" in the U.S. nuclear industry. The plant generates virtually no greenhouse gas emissions and "we go to great lengths to minimize our impact to the environment," Swenson said. The meetings were aimed at getting public comment on potential environmental impacts linked to Oyster Creek license renewal and what the NRC should address in its environmental review, according to NRC officials. A variety of concerns Speakers expressed concerns about the impact of plant cooling water intakes and discharges on aquatic life, spent fuel storage, the threat of an airplane attack, the evacuation plan and potential radioactive releases, among other issues. Some called for the plant's shutdown. Others said the environmental impact of a non-nuclear replacement power plant would exceed that of Oyster Creek, which should operate until 2029. The plant is the oldest operating commercial nuclear plant in the nation; it began running in 1969. The license renewal process focuses on plant safety and environmental impact during a 20-year extension. Other issues, such as the evacuation plan and security, are addressed on an ongoing basis, NRC officials have said. "This needs to be broader than just something about whether the fish die," said Kelly McNicholas, conservation coordinator for the Sierra Club's New Jersey chapter. "It needs to look at the environmental health of the people in the community." According to an NRC document, the environmental review will determine "whether or not the adverse environmental impacts of license renewal . . . are so great that preserving the option of license renewal for energy planning decision makers would be unreasonable," according to an NRC document. "Simply put, is a license renewal acceptable from an environmental standpoint," said Michael T. Masnik, senior project manager with the NRC who is coordinating the environmental review. Frederick W. Polaski, license renewal manager for Exelon Nuclear, said, "Oyster Creek can operate safely for 60 years," and its impacts on the environment are small. A 600-megawatt non-nuclear power plant at the site or elsewhere would have a greater environmental impact than the continued operation of Oyster Creek, he said. But Thomas J. Cervasio, chairman of EnviroWatch, said the plant should be shut down, partly because there is no safe storage of nuclear waste. John Generalli, a Berkeley resident who has lymphoma, asked if spent fuel rods in the spent fuel pool are a danger and "when are they going to get (them) out?" Tom Jackson of Manchester said "a cooling tower should be built." Cooling tower debate State environmental officials would like the Oyster Creek plant to build a closed-cycle cooling water system with cooling towers to reduce water intake by more than 95 percent. The current once-through kills millions of fish, shrimp and other aquatic life each year, according to estimates cited by the DEP. But Wayne Romberg, a project manager at the plant, said "as a resident, I don't want a cooling tower" and the salt spray from it. The evening session featured more of the same, with some calling for the plant's renewal and others voicing opposition. David Most, a candidate for Township Committee in Lacey, said the power plant has no negative environmental impact. He noted that the population of striped bass in Barnegat Bay, which had declined in years past due to overfishing, would not have regrouped if the plant were a threat to the bay. Brick resident Jeff Brown questioned whether there were firm standards in place that determine the success of relicensing application, or if problems are simply addressed as they are identified so that the renewal application can be granted. Lacey resident Terry Matthews countered that the NRC has benchmarks in place that set forth what the appropriate response to any problems are. He said the people calling for the plant to be shut down are "in the wrong ballpark here." "We need to just let the NRC and the plant people do their job," he said. Some people expressed concern about whether plans for evacuating municipalities within 10 miles of the plant are adequate to address the needs of the area's current and future population. "The safe operation of Oyster Creek is our top priority," Swenson said. This story includes material from previous Press stories. Todd B. Bates: (732) 643-4237 or tbates@app.com [E-mail] Copyright © 2005 Asbury Park Press. All rights reserved. ***************************************************************** 11 JOURNAL NEWS: Indian Point inspections to increase By GREG CLARY gclary@thejournalnews.com (Original publication: November 2, 2005) BUCHANAN — Federal nuclear regulators have followed through on a promise made last week to Sen. Hillary Rodham Clinton to increase scrutiny at Indian Point, an extra effort to address a radioactive water leak at the site and the reliability of the nuclear plants' emergency siren notification system. The Nuclear Regulatory Commission announced Monday it will carry out additional inspections and wrote a "deviation memo" that notes that the extra oversight will be undertaken because of the two problems and despite the plants' overall high marks in 2003 and 2004 for safe operation. "In the case of Indian Point, the staff considers it prudent to apply additional inspection focus to specific areas," said NRC Region I Administrator Samuel J. Collins, "even though licensee performance in these areas has not crossed any specific thresholds mandating additional regulatory oversight." The change grew out of a meeting last week between NRC Chairman Nils Diaz and Clinton, D-N.Y., in which the senator outlined her concerns that a two-month-old leak could reach nearby drinking water sources, and the ongoing problem of a 156-siren emergency notification system that malfunctioned six times in the last three months. "Now, the test will be in whether deeds meet words, and I hope that the NRC will keep its commitment to the communities around Indian Point," Clinton said yesterday. "This is an important step forward, but I will continue to monitor the situation to ensure that the NRC and Entergy address both the spent fuel pool leaks and the deficiencies of the emergency notification system." In late September, the NRC began a special inspection at Indian Point into leaking from the spent fuel pool area at the Indian Point 2 nuclear power plant. The leak is about 2 liters of radioactive water per day and does not pose any immediate health or safety concerns for the public or plant workers, agency officials said. Last month, tritium was detected in six of nine on-site locations. No tritium has been detected off-site. NRC officials dispatched to monitor the leak and repair efforts are expected to remain on-site for several more weeks. Copyright 2005 The Journal News, a Gannett Co. Inc. newspaper ***************************************************************** 12 NRC: In the Matter of Entergy Operations, Inc., Grand Gulf Nuclear FR Doc 05-21940 [Federal Register: November 2, 2005 (Volume 70, Number 211)] [Notices] [Page 66474-66475] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr02no05-140] Station, Independent Spent Fuel Storage Installation; Order Modifying License (Effective Immediately) AGENCY: Nuclear Regulatory Commission. ACTION: Issuance of Order for Implementation of Interim Safeguards and Security Compensatory Measures. FOR FURTHER INFORMATION CONTACT: Paul W. Harris, Senior Project Manager, Licensing and Inspection Directorate, Spent Fuel Project Office, Office of Nuclear Material Safety and Safeguards, U.S. Nuclear Regulatory Commission, Rockville, MD 20852. Telephone: (301) 415-1169; fax number: (301) 415-8555; e-mail PWH1@nrc.gov. SUPPLEMENTARY INFORMATION: I. Introduction Pursuant to 10 CFR 2.106, the U.S. Nuclear Regulatory Commission (NRC) is providing notice in the matter of Grand Gulf Nuclear Station Independent Spent Fuel Storage Installation Order Modifying License (Effective Immediately). II. Further Information I Entergy Operations, Inc. (Entergy) has been issued a general license by the U.S. Nuclear Regulatory Commission (NRC or the Commission) authorizing storage of spent fuel in an independent spent fuel storage installation (ISFSI) in accordance with the Atomic Energy Act of 1954, 10 CFR Part 50, and 10 CFR Part 72. This Order is being issued to Entergy who has identified near-term plans to store spent fuel in an ISFSI under the general license provisions of 10 CFR Part 72. The Commission regulations at 10 CFR 72.212(b)(5) and 10 CFR 73.55(h)(1) require Entergy to maintain safeguards contingency plan procedures in accordance with 10 CFR Part 73, Appendix C. Specific safeguards requirements are contained in 10 CFR 73.55. II On September 11, 2001, terrorists simultaneously attacked targets in New York, NY, and Washington, DC, utilizing large commercial aircraft as weapons. In response to the attacks and intelligence information subsequently obtained, the Commission issued a number of Safeguards and Threat Advisories to its licensees in order to strengthen licensees' capabilities and readiness to respond to a potential attack on a nuclear facility. The Commission has also communicated with other Federal, State, and local government agencies and industry representatives to discuss and evaluate the current threat environment in order to assess the adequacy of security measures at licensed facilities. In addition, the Commission has been conducting a comprehensive review of its safeguards and security programs and requirements. As a result of its consideration of current safeguards and security plan requirements, as well as a review of information provided by the intelligence community and other governmental agencies, the Commission has determined that certain compensatory measures are required to be implemented by licensees as prudent, interim measures, to address the current threat environment in a consistent manner throughout the nuclear ISFSI community. Therefore, the Commission is imposing requirements, as set forth in Attachment 1 \1\ of this Order, on Entergy who has indicated near-term plans to store spent fuel in an ISFSI under the general license provisions of 10 CFR Part 72. These interim requirements, which supplement existing regulatory requirements, will provide the Commission with reasonable assurance that the public health and safety and common defense and security continue to be adequately protected in the current threat environment. These requirements will remain in effect until the Commission determines otherwise. ----------------------------------------------------------------- ---------- \1\ Attachment 1 contains safeguards information and will not be released to the public. ----------------------------------------------------------------- ---------- The Commission recognizes that some measures may not be possible or necessary, or may need to be tailored to accommodate the specific circumstances existing at Entergy's facility to achieve the intended objectives and avoid any unforeseen effect on the safe storage of spent fuel. In order to provide assurance that licensees are implementing prudent measures to achieve a consistent level of protection to address the current threat environment, the Commission concludes that security measures must be embodied in an Order consistent with the established regulatory framework. Entergy's general license issued pursuant to 10 CFR 72.210 shall be modified to include the requirements identified in Attachment 1 to this Order. In addition, pursuant to 10 CFR 2.202, the Commission finds that in the circumstances described above, the public health, safety, and interest require that this Order be effective immediately. III Accordingly, pursuant to Sections 103, 104, 161b, 161i, 161o, 182, and 186 of the Atomic Energy Act of 1954, as amended, and the Commission's regulations in 10 CFR 2.202 and 10 CFR parts 50, 72, and 73, it is hereby ordered, effective immediately, that your general license is modified as follows: A. Entergy shall, notwithstanding the provisions of any Commission regulation or license to the contrary, comply with the requirements described in Attachment 1 to this Order except to the extent that a more stringent requirement is set forth in their security plan. Entergy shall immediately start implementation of the requirements in Attachment 1 to the Order and shall complete implementation before April 26, 2006, or the first day that spent fuel is initially placed in the ISFSI, whichever is earlier. B. 1. Entergy shall, within twenty (20) days of the date of this Order, notify the Commission: (1) If they are unable to comply with any of the requirements described in Attachment 1, (2) if compliance with any of the requirements is unnecessary in their specific circumstances, or (3) if implementation of any of the requirements would cause the licensee to be in violation of the provisions of any Commission regulation or the facility license. The notification shall provide the licensee's justification for seeking relief from or variation of any specific requirement. 2. If Entergy considers that implementation of any of the requirements described in Attachment 1 to this Order would adversely impact the safe storage of spent fuel, Entergy must notify the Commission, within twenty (20) days of this Order, of the adverse safety impact, the basis for its determination that the requirement has an adverse safety impact, and either a proposal for achieving the same objectives specified in the Attachment 1 requirement(s) in question, or a schedule for modifying the facility to address the adverse safety condition. If neither approach is appropriate, Entergy must supplement its response to [[Page 66475]] Condition B.1 of this Order to identify the condition as a requirement with which it cannot comply, with attendant justifications as required in Condition B.1. C.1. Entergy shall, within twenty (20) days of the date of this Order, submit to the Commission, a schedule for achieving compliance with each requirement described in Attachment 1. 2. Entergy shall report to the Commission when they have achieved full compliance with the requirements described in Attachment 1. D. Notwithstanding the provisions of 10 CFR 72.212(b)(5), all measures implemented or actions taken in response to this Order shall be maintained until the Commission determines otherwise. Entergy's responses to Conditions B.1, B.2, C.1, and C.2, shall be submitted in accordance with 10 CFR 72.4. In addition, submittals that contain Safeguards Information shall be properly marked and handled in accordance with 10 CFR 73.21. The Director, Office of Nuclear Material Safety and Safeguards may, in writing, relax or rescind any of the above conditions upon demonstration by Entergy of good cause. IV In accordance with 10 CFR 2.202, Entergy must, and any other person adversely affected by this Order may, submit an answer to this Order, and may request a hearing on this Order, within twenty (20) days of the date of this Order. Where good cause is shown, consideration will be given to extending the time to request a hearing. A request for extension of time in which to submit an answer or request a hearing must be made in writing to the Director, Office of Nuclear Material Safety and Safeguards, and the Director, Office of Enforcement, U.S. Nuclear Regulatory Commission, Washington, DC 20555, and include a statement of good cause for the extension. The answer may consent to this Order. Unless the answer consents to this Order, the answer shall, in writing and under oath or affirmation, specifically set forth the matters of fact and law on which the licensee or other person adversely affected relies and the reasons as to why the Order should not have been issued. Any answer or request for a hearing shall be submitted to the Secretary, Office of the Secretary of the Commission, U.S. Nuclear Regulatory Commission, ATTN: Rulemakings and Adjudications Staff, Washington, DC 20555. Copies also shall be sent to the Director, Office of Nuclear Material Safety and Safeguards, U.S. Nuclear Regulatory Commission, Washington, DC 20555; to the Director, Office of Enforcement at the same address; to the Assistant General Counsel for Materials Litigation and Enforcement at the same address, to the Regional Administrator for NRC Region IV at 611 Ryan Plaza Drive, Suite 400, Arlington, TX 76011-4005; and to the licensee if the answer or hearing request is by a person other than the licensee. Because of potential disruptions in delivery of mail to United States Government offices, it is requested that answers and requests for hearing be transmitted to the Secretary of the Commission, either by means of facsimile transmission to 301-415-1101, or by e-mail to hearingdocket@nrc.gov and also to the Office of the General Counsel, either by means of facsimile transmission to 301-415-3725, or by e-mail to OGCMailCenter@nrc.gov. If a person other than Entergy requests a hearing, that person shall set forth with particularity the manner in which his interest is adversely affected by this Order and shall address the criteria set forth in 10 CFR 2.714(d). If a hearing is requested by Entergy or a person whose interest is adversely affected, the Commission will issue an Order designating the time and place of any hearing. If a hearing is held, the issue to be considered at such a hearing shall be whether this Order should be sustained. Pursuant to 10 CFR 2.202(c)(2)(i), Entergy may, in addition to demanding a hearing, at the time the answer is filed or sooner, move the presiding officer to set aside the immediate effectiveness of the Order on the grounds that the Order, including the need for immediate effectiveness, is not based on adequate evidence but on mere suspicion, unfounded allegations, or error. In the absence of any request for hearing, or written approval of an extension of time in which to request a hearing, the provisions specified in Section III above shall be final twenty (20) days from the date of this Order without further order or proceedings. If an extension of time for requesting a hearing has been approved, the provisions specified in Section III shall be final when the extension expires if a hearing request has not been received. An answer or a request for hearing shall not stay the immediate effectiveness of this order. For the Nuclear Regulatory Commission. Dated this 26th day of October 2005. Jack R. Strosnider, Director, Office of Nuclear Material Safety and Safeguards. [FR Doc. 05-21940 Filed 11-1-05; 8:45 am] BILLING CODE 7590-01-P ***************************************************************** 13 NRC: In the Matter of Entergy Operations, Inc., Grand Gulf Nuclear FR Doc E5-6055 [Federal Register: November 2, 2005 (Volume 70, Number 211)] [Notices] [Page 66475-66477] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr02no05-141] Station Independent Spent Fuel Storage Installation, Order Modifying License (Effective Immediately) AGENCY: Nuclear Regulatory Commission. ACTION: Issuance of Order for Implementation of Additional Security Measures Associated with Access Authorization. FOR FURTHER INFORMATION CONTACT: Paul W. Harris, Senior Project Manager, Licensing and Inspection Directorate, Spent Fuel Project Office, Office of Nuclear Material Safety and Safeguards, U.S. Nuclear Regulatory Commission, Rockville, MD 20852. Telephone: (301) 415-1169; fax number: (301) 415-8555; e-mail . SUPPLEMENTARY INFORMATION: I. Introduction Pursuant to 10 CFR 2.106, the U.S. Nuclear Regulatory Commission (NRC) is providing notice in the matter of Grand Gulf Nuclear Station Independent Spent Fuel Storage Installation Order Modifying License (Effective Immediately). II. Further Information I Entergy Operations, Inc. (Entergy) holds a license issued by the U.S. Nuclear Regulatory Commission (NRC or the Commission) authorizing the operation of an Independent Spent Fuel Storage Installation (ISFSI) in accordance with the Atomic Energy Act of 1954 and Title 10 of the Code of Federal Regulations (10 CFR) part 50 and 10 CFR part 72. Commission regulations at 10 CFR 72.212(b)(5) and 10 CFR 73.55(h)(1) require Entergy to have a safeguards contingency plan to respond to threats of radiological sabotage and to protect the spent fuel against the threat of radiological sabotage. Inasmuch as an insider has an opportunity equal to or greater than any other person to commit radiological sabotage, the Commission has [[Page 66476]] determined these measures to be prudent. This Order has been issued to all licensees who currently store spent fuel or have identified near- term plans to store spent fuel in an ISFSI. II On September 11, 2001, terrorists simultaneously attacked targets in New York, NY, and Washington, DC, utilizing large commercial aircraft as weapons. In response to the attacks and intelligence information subsequently obtained, the Commission issued a number of Safeguards and Threat Advisories to its licensees in order to strengthen licensees' capabilities and readiness to respond to a potential attack on a nuclear facility. On October 16, 2002, the Commission issued Orders to the licensees of operating ISFSIs to put the actions taken in response to the Advisories in the established regulatory framework and to implement additional security enhancements which emerged from the NRC's ongoing comprehensive review. The Commission has also communicated with other Federal, State, and local government agencies and industry representatives to discuss and evaluate the current threat environment in order to assess the adequacy of security measures at licensed facilities. In addition, the Commission has been conducting a comprehensive review of its safeguards and security programs and requirements. As a result of its consideration of current safeguards and security requirements, as well as a review of information provided by the intelligence community, the Commission has determined that certain additional security measures are required to address the current threat environment in a consistent manner throughout the nuclear ISFSI community. Therefore, the Commission is imposing requirements, as set forth in Attachment 1\1\ of this Order, on all licensees of these facilities. These requirements, which supplement existing regulatory requirements, will provide the Commission with reasonable assurance that the public health and safety and common defense and security continue to be adequately protected in the current threat environment. These requirements will remain in effect until the Commission determines otherwise. \1\ Attachment 1 contains SAFEGUARDS INFORMATION and will not be released to the public. The Commission recognizes that licensees may have already initiated many of the measures set forth in Attachment 1 to this Order in response to previously issued advisories, the October 2002 Order, or on their own. It also recognizes that some measures may not be possible or necessary at some sites, or may need to be tailored to accommodate the specific circumstances existing at the licensee's facility to achieve the intended objectives and avoid any unforeseen effect on the safe storage of spent fuel. Although the additional security measures implemented by licensees in response to the Safeguards and Threat Advisories have been adequate to provide reasonable assurance of adequate protection of public health and safety, the Commission concludes that these actions must be supplemented further because the current threat environment continues to persist. Therefore, it is appropriate to require certain additional security measures and these measures must be embodied in an Order, consistent with the established regulatory framework. In order to provide assurance that Entergy is implementing prudent measures to achieve a consistent level of protection to address the current threat environment, Entergy's general license issued pursuant to 10 CFR 72.210 shall be modified to include the requirements identified in Attachment 1 to this Order. In addition, pursuant to 10 CFR 2.202, the Commission finds that in the circumstances described above, the public health, safety, and interest require that this Order be immediately effective. III Accordingly, pursuant to Sections 53, 103, 104, 161b, 161i, 161o, 182, and 186 of the Atomic Energy Act of 1954, as amended, and the Commission's regulations in 10 CFR 2.202 and 10 CFR parts 50, 72, and 73, It Is Hereby Ordered, Effective Immediately, That Your General License Is Modified as Follows: A. Entergy shall, notwithstanding the provisions of any Commission regulation or license to the contrary, comply with the requirements described in Attachment 1 to this Order except to the extent that a more stringent requirement is set forth in the Entergy's security plan. Entergy shall immediately start implementation of the requirements in Attachment 1 to the Order and shall complete implementation no later than April 26, 2006, with the exception of the additional security measures B.4, which shall be implemented no later than October 26, 2006, or the first day that spent fuel is initially placed in the ISFSI, whichever is earlier. B. 1. Entergy shall, within twenty (20) days of the date of this Order, notify the Commission: (1) If it is unable to comply with any of the requirements described in Attachment 1, (2) if compliance with any of the requirements is unnecessary in their specific circumstances, or (3) if implementation of any of the requirements would cause Entergy to be in violation of the provisions of any Commission regulation or the facility license. The notification shall provide Entergy's justification for seeking relief from or variation of any specific requirement. 2. If Entergy considers that implementation of any of the requirements described in Attachment 1 to this Order would adversely impact the safe storage of spent fuel, Entergy must notify the Commission, within twenty (20) days of this Order, of the adverse safety impact, the basis for its determination that the requirement has an adverse safety impact, and either a proposal for achieving the same objectives specified in the Attachment 1 requirements in question, or a schedule for modifying the facility to address the adverse safety condition. If neither approach is appropriate, Entergy must supplement its response to Condition B.1 of this Order to identify the condition as a requirement with which it cannot comply, with attendant justifications as required under Condition B.1. C. 1. Entergy shall, within twenty (20) days of this Order, submit to the Commission a schedule for achieving compliance with each requirement described in Attachment 1. 2. Entergy shall report to the Commission when they have achieved full compliance with the requirements described in Attachment 1. D. Notwithstanding the provisions of 10 CFR 72.212(b)(5), all measures implemented or actions taken in response to this Order shall be maintained until the Commission determines otherwise. Entergy's response to Conditions B.1, B.2, C.1, and C.2, above shall be submitted in accordance with 10 CFR 72.4. In addition, submittals that contain Safeguards Information shall be properly marked and handled in accordance with 10 CFR 73.21. The Director, Office of Nuclear Material Safety and Safeguards, may, in writing, relax or rescind any of the above conditions upon demonstration by Entergy of good cause. IV In accordance with 10 CFR 2.202, Entergy must, and any other person [[Page 66477]] adversely affected by this Order may, submit an answer to this Order, and may request a hearing on this Order, within twenty (20) days of the date of this Order. Where good cause is shown, consideration will be given to extending the time to request a hearing. A request for extension of time in which to submit an answer must be made in writing to the Director, Office of Nuclear Material Safety and Safeguards, and the Director, Office of Enforcement, U.S. Nuclear Regulatory Commission, Washington, DC 20555, and include a statement of good cause for the extension. The answer may consent to this Order. Unless the answer consents to this Order, the answer shall, in writing and under oath or affirmation, specifically set forth the matters of fact and law on which the licensee or other person adversely affected relies and the reasons as to why the Order should not have been issued. Any answer or request for a hearing shall be submitted to the Secretary, Office of the Secretary of the Commission, U.S. Nuclear Regulatory Commission, Attn: Rulemakings and Adjudications Staff, Washington, DC 20555. Copies also shall be sent to the Director, Office of Nuclear Material Safety and Safeguards, U.S. Nuclear Regulatory Commission, Washington, DC 20555; to the Director, Office of Enforcement at the same address; to the Assistant General Counsel for Materials Litigation and Enforcement at the same address, to the Regional Administrator for NRC Region IV at 611 Ryan Plaza Drive, Suite 400, Arlington, TX 76011-4005; and to the licensee if the answer or hearing request is by a person other than the licensee. Because of possible disruptions in delivery of mail to United States Government offices, it is requested that requests for a hearing be transmitted to the Secretary of the Commission either by means of facsimile transmission to 301-415-1101 or by e-mail to and also to the Office of General Counsel either by means of facsimile transmission to 301-415-3725 or by e-mail to . If a person other than Entergy requests a hearing, that person shall set forth with particularity the manner in which his/her interest is adversely affected by this Order and shall address the criteria set forth in 10 CFR 2.714(d). If a hearing is requested by Entergy or a person whose interest is adversely affected, the Commission will issue an Order designating the time and place of any hearing. If a hearing is held, the issue to be considered at such hearing shall be whether this Order should be sustained. Pursuant to 10 CFR 2.202(c)(2)(I), Entergy may, in addition to demanding a hearing at the time the answer is filed or sooner, move the presiding officer to set aside the immediate effectiveness of the Order on the grounds that the Order, including the need for immediate effectiveness, is not based on adequate evidence but on mere suspicion, unfounded allegations or error. In the absence of any request for hearing or written approval of an extension of time in which to request a hearing, the provisions specified in Section III above shall be final twenty (20) days from the date of this Order without further order or proceedings. If an extension of time for requesting a hearing has been approved, the provisions specified in Section III shall be final when the extension expires, if a hearing request has not been received. An Answer or a Request for Hearing Shall Not Stay the Immediate Effectiveness of This Order. For the Nuclear Regulatory Commission. Dated this 26th day of October 2005. Jack R. Strosnider, Director, Office of Nuclear Material Safety and Safeguards. [FR Doc. E5-6055 Filed 11-1-05; 8:45 am] BILLING CODE 7590-01-P ***************************************************************** 14 NRC: Notice of Public Scoping Meeting and Solicitation of Scoping FR Doc E5-6056 [Federal Register: November 2, 2005 (Volume 70, Number 211)] [Notices] [Page 66472-66473] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr02no05-138] Comments Related to the Standard Review Plan for Waste Determination Reviews AGENCY: United States Nuclear Regulatory Commission (NRC). ACTION: Notice; Scoping meeting and opportunity to comment. SUMMARY: The NRC announces its intent to conduct a public scoping meeting to present an overview of the proposed outline for the Standard Review Plan (SRP) for Waste Determination Reviews and to accept oral and written public comments. The meeting date, time and location are listed below: Meeting Date: Thursday, November 10, 2005. Meeting Location: Hilton Gaithersburg, 620 Perry Parkway, Gaithersburg, Maryland 20877, 301-977-8900, http://www.hilton.com/ en/ hi/hotels/index.jhtml; jsessionid= LMCCLDIIWRZ1KCSG BIX2VCQKIYFCXUUC? ctyhocn=GAIGHHF. SRP Meeting Agenda: 12:30 p.m.-1 p.m. Meeting Registration 1:00 p.m.-1:15 p.m. Welcome & Introductory Remarks 1:15 p.m.-1:45 p.m. NRC Roles & Responsibilities 1:45 p.m.-2:15 p.m. SRP Overview 2:15 p.m.-2:30 p.m. Questions 2:30 p.m.-2:45 p.m. Break 2:45 p.m.-4:45 p.m. Comments on the Scope of the SRP 4:45 p.m.-5 p.m. Closing Remarks Background On October 9, 2004, the Ronald W. Reagan National Defense Authorization Act for Fiscal Year 2005 (NDAA) was passed by Congress and was signed by the President on October 28, 2004. Section 3116 of the NDAA allows the U.S. Department of Energy (DOE) to determine that certain waste stemming from reprocessing of spent nuclear fuel is not high-level-waste (HLW). However, the NDAA is applicable only in the States of South Carolina and Idaho and does not apply to waste transported out of these States. The NDAA requires that: (1) DOE consult with NRC on all of its waste determinations in South Carolina and Idaho, and (2) NRC, in coordination with the State, monitor disposal actions taken by DOE for the purpose of assessing compliance with NRC regulations in 10 CFR part 61, subpart C. If the NRC determines that any disposal actions taken by DOE are not in compliance, the NDAA requires NRC to inform DOE, the affected State, and congressional subcommittees. In addition to NDAA activities conducted at the Savannah River Site (SRS) and Idaho National Laboratory (INL), DOE may make similar waste determinations at its Hanford site and at the West Valley Demonstration Project (WVDP) and may request NRC to provide technical reviews of those determinations. The staff has described its plans for implementing its activities under the NDAA in SECY-05-0073 and the Commission approved the plans in the corresponding Staff Requirements Memorandum dated June 30, 2005. The NRC staff is developing a waste determination Standard Review Plan (SRP) to provide guidance to staff on reviewing waste determination information and analyses. This meeting is an opportunity for interested parties to submit comments on the scope of the SRP. The draft SRP will also be published for public comment and the comments received will be considered by the staff during development of the final SRP. Draft SRP Outline Introduction Background for SRP How To Use the SRP Updating the SRP Structure of the SRP Introduction to WIR and NDAA Role of NRC in NDAA Site-Specific and General Information Site-Specific System Description Information Applicable Waste Criteria Prior Waste Determinations Site-Specific Criteria for West Valley (West Valley Final Policy Statement), Hanford (DOE Order 435.1), Savannah River and Idaho National Laboratory (National Defense Authorization Act, Section 3116) Removal of Radionuclides Concentration Limits Compliance With Performance Objectives of 10 CFR Part 61, Subpart C [[Page 66473]] Disposal Modeling Approach Source-Term Development Climate and Infiltration Engineered Barriers and Near-Field Radionuclide Transport Far-Field Radionuclide Transport Modifying Scenarios, Pathways, and Receptor Groups Conceptual Models Computer Codes/Models Input Parameter Values Evaluating Model Results ALARA Analyses References Protection of Individuals During Operations Inadvertent Intrusion Scenarios for Modeling Site Stability Quality Assurance Program Monitoring Monitoring Methods Demonstrating Compliance With 10 CFR 61, Subpart C Noncompliance Reports Appendices The SRP scoping meeting officially begins at 1 p.m. and will include: (1) A presentation summarizing NRC roles and responsibilities, (2) an overview of the proposed draft SRP, and (3) an opportunity for interested government agencies, organizations, and individuals to provide comments on the scope of the SRP. This meeting will be transcribed by a court reporter. Persons wishing to provide oral comments will be asked to register at the meeting entrance. Individual oral comments may have to be limited to 5 minutes each, depending upon the number of persons who register. Please note that comments do not have to be provided at the public meeting and may be submitted at any time before November 25, 2005, as described in the DATES and ADDRESSES sections of this notice. DATES: The public comment period on the SRP begins with publication of this notice and continues until November 25, 2005. Written comments should be submitted as described in the ADDRESSES section of this notice. Comments submitted by mail should be postmarked by that date to ensure consideration. Comments received or postmarked after that date will be considered to the extent practical. A public meeting to discuss the proposed draft SRP will be held on November 10, 2005 as described in the SUMMARY section of this notice. ADDRESSES: Members of the public are invited and encouraged to submit comments to the Division of Waste Management and Environmental Protection, Low-Level Waste Section Chief, Mail Stop T7-J08, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001. Please note Docket No. POOM-32, PROJ0734, PROJ0735, PROJ0736 when submitting comments. Comments will also be accepted by e-mail at AHB1@nrc.gov or by facsimile to (301) 415-5397, Attention: Anna Bradford with a subject line containing the document identifier: SRP. FOR FURTHER INFORMATION CONTACT: For questions related to the Standard Review Plan, please contact Anna Bradford at (301) 415-5228. For public scoping meeting questions, please contact Michele O'Shaughnessy at (301) 415-6659. Dated at Rockville, Maryland, this 26th day of October 2005. For the Nuclear Regulatory Commission. Ryan Whited, Chief, Low-Level Waste Section, Environmental and Performance Assessment Directorate, Division of Waste Management and Environmental Protection, Office of Nuclear Material Safety and Safeguards. [FR Doc. E5-6056 Filed 11-1-05; 8:45 am] BILLING CODE 7590-01-P ***************************************************************** 15 Hudson Valley News: NRC plans enhanced oversight of Indian Point Wednesday, November 2, 2005 Senator Hillary Clinton yesterday welcomed the formal announcement by the Nuclear Regulatory Commission that it would be conducting enhanced oversight of Indian Point, but said she would continue to monitor the progress being made in investigating recent leaks found near the spent fuel pools at the Indian Point power plant, as well as continued problems associated with the plants emergency notification system. The senator also joined calls yesterday for the U.S. Coast Guard to complete a comprehensive assessment of the vulnerability of Indian Point and all nuclear plants around the country. Senator Clinton was notified of the commitment to enhanced oversight from the NRC last week by Chairman Nils Diaz. The chairman committed that the NRC would be implementing a provision Clinton inserted in the energy bill by issuing detailed orders to Entergy, Indian Points owner, in January to require them to back up their emergency notification system. Clinton yesterday also joined calls by Congressman Eliot Engel for the U.S. Coast Guard to complete a comprehensive assessment of the vulnerability of Indian Point and all nuclear plants around the country. Last year, Congress passed the Coast Guard Authorization Act which included a provision supported by Clinton that requires the Coast Guard to conduct vulnerability assessments of all U.S. nuclear power plants. The assessment was designed to focus on the vulnerability of the plants to attack from the water. The bill required the Coast Guard to assess the vulnerability of the Fitzpatrick and Nine Mile Point plants in Oswego, the Ginna plant in Rochester and the Indian Point plants in Buchanan, as well as plants across the nation. HEAR today's news on MidHudsonRadio.com, the Hudson Valley's only Internet radio news report. ***************************************************************** 16 technicianonline.com: Reactor mystifies campus 11.02.2005 Tyler Dukes People often fear the mysterious. And to the casual student, the PULSTAR nuclear reactor located in Burlington Complex is definitely mysterious. Housed in a 15,000 gallon tank constructed with six-foot thick, high-density concrete, the reactor emits a bright blue glow as it generates one megawatt of thermal energy. For many students, like freshman in electrical engineering Josh Brown, knowledge of the reactor is “very limited.” And he's not alone. "Honestly, I don't know anything about it," Brandon Crawford, senior in wood products, said. "All I've heard was that it's there." "I really don't know a whole lot about it," Matthew Holmes, junior in English, said gazing up at the reactor's chimney. "I know if it blows up, it wouldn't take out too much." But despite its mystery, a stringent set of security measures, heavily regulated by the Nuclear Regulatory Commission, have allowed the facility to operate “without incident for 35 years,” according to Engineering and Operations Manager Andrew Cook. Regulated Research Although the power generated by the reactor is around 3,000 times less than the Shearon-Harris nuclear plant in Wake County, the operation of a facility that uses radioactive material is no haphazard business. In an industry heavily regulated by the NRC, nuclear engineers on campus must conduct their research with special emphasis not just on safety, but on security. Every reactor, for example, has a physical security plan, approved by the NRC. "It's what the facility will do to protect the material inside," Cook said. Facilities also have an NRC-approved emergency plan, which spells out procedures for "every credible scenario," according to Cook. According to Gerald Wicks, reactor health physicist, the nuclear program re-examines these plans every year to evaluate the effectiveness of the security measures in place. "You evaluate what is credible,” Wicks said. “You can't evaluate what's incredible, like getting hit by a meteor." The threat of terrorism has had its effect on the reactor program, most notably with the change in tour policy. According to Cook, prior to 9/11, the program allowed open tours of the reactor. Afterward, the NRC issued "compensatory action letters," requiring a reassessment of the reactor's safety plan and an increase in security measures. "We implemented these and went above and beyond," Cook said. He said the current tour policy requires a two-week advance notice for visits to the reactor. "It has to be for a legitimate reason...to promote and enhance science,” Cook said. “We review and approve the tour itself." Controversial Criticism Despite the regulations, ABC News recently targeted campus research reactors in an investigation, sending out a crew of undercover reporters to test the security measures in the 25 different nuclear research reactors in the country, including the reactor at N.C. State. "Among our findings, unmanned guard booths, unlocked doors and again and again easy access with no background checks, no metal detectors, to reactors using the most dangerous materials in the world," ABC News' chief investigative correspondent Brian Ross said of the reactors during the program. Although the report, aired on Oct. 13, did not reference the University reactor specifically, the program's “Loose Nukes” Web site did report on its findings in Burlington, pointing to an unlocked door to the Nuclear Materials Laboratory as well as a picture of the reactor schematic on the wall. But according to Cook, the report's findings on NCSU were inconclusive. He said the schematic on the wall was from an old, decommissioned reactor and that the laboratory does not actually contain any radioactive material. The report was also heavily criticized by the Nuclear Energy Institute in an Oct. 14 press release. “ABC sensationalized the findings of its investigation by failing to assess the difficulty that even suicidal terrorists would face in trying to remove heavy, highly radioactive material from the small research reactors,” the release stated. Wicks said although other schools may have “used some bad judgment” and failed to follow some procedures, one of the big issues with the report was that they did not clearly define the rules and regulations outlined by the NRC. “The risk issue was not communicated – they overplayed it,” Wicks said. “Just because they park their van near a barricade, it doesn't mean that's a failure of security.” The NEI specifically focused on one incident where Ross referenced the reactor at Texas A, stating that “an explosive thrown in [the reactor] could be the beginning of a dirty bomb.” “The bottom line is that throwing a small bomb into a reactor pool is likely to damage the reactor core, and likely to cause some radioactivity to be released. However, I would not expect this contamination to pose a health risk to people nearby,” Andrew Karam, director of radiation safety at the Rochester Institute of Technology, said in the release. Cook said the effect of an accident or explosion on the outside environment at NCSU would also be minimal. “The dose to the public is negligible,” Cook said. 'Piece of mind' Even in normal operation, which Wicks said is “all the time,” employees and staff are required to strictly adhere to safety and security requirements. All employees are required to carry thermo-luminescent devices that detect both gamma and neutron radiation. These badges, issued by NCSU's own Radiation Safety Division, keep track of the amount of radiation employees are exposed to and ensure their safety. The badges are sent off to a laboratory quarterly for examination. Similar devices can be found in dentist and doctors offices with those who operate X-rays. Visitors to the reactor also receive pocket ion chambers. These pen-sized tubes contain visual scale that can instantaneously measure the amount of radiation visitors to the reactor are exposed to. Cook said this level is always zero. "From a tour perspective, it's a piece of mind for the visitor, but it's also to make sure it's safe," Cook said. Safe for the 'foot soldier' Even on the back-end, University officials are serious about dealing with radioactive materials. Bruce Stewart is the campus hazardous waste specialist and has been trained to be responsible for hazardous and low-level waste disposal from labs all over campus. “There's a certain amount of waste the reactor generates and I'm responsible for the disposal of that waste,” Stewart said. He said the campus reactor generates a small amount of waste, compared to the other labs around campus. Because it is not cost effective to ship out the material, stored in large drums, as soon as it is received, Stewart said the waste is stored in the environmental heath and safety building, a concrete block building surrounded by a locked fence. He said the material could be dangerous, under certain conditions of course. “It's dangerous to the public if you're stupid,” Stewart said. “They'd have to physically stick their hands in radioactive waste.” He said the environment's not dangerous to the workers either. “If you walked around with a [radioactivity] meter, you would get almost background on the meter,” Stewart said. Stewart said employees who work with the material go through extensive training for their positions and periodically participate in training simulations with Raleigh Hazardous materials. In the event of a large-scale emergency, he said, there is an emergency-response network in Wake County “equivalent to FEMA.” “Because of this, I can be used as a foot soldier,” Stewart said. “I stand around and wait until someone tells me where to go.” Staying Power As its fourth reactor, the PULSTAR marks more than 50 years of history with NCSU's nuclear program, which Cook said, was the first in the nation. The department boasts projects with funding from the U.S. Department of Energy and the National Science Foundation, among others, with research affecting fields from food sterilization to medical imaging and textiles. And although many students may not be familiar with the bright-blue spectrum of on-campus uranium, Cook said the 30-year-old glow won't be fading any time soon. “There's no reason to suspect why [the reactor] wouldn't be here for another 30 years.” North Carolina State University's Student Newspaper Since 1920 CONTACT US | JOIN THE STAFF | ADVERTISE PAGE ONE | SEARCH © 2000-2004 NCSU SMA. All Rights Reserved. ***************************************************************** 17 Business Gazette: NUCLEAR SELL-OFF: EFFECTS ON SUPPLY CHAIN Published in Business Gazette on Wednesday, November 2nd 2005 Dog Holden, chief executive of West Cumbria Development Agency, looks at the effects on the West Cumbria supply chain of a possible sale of British Nuclear Group BRITISH Nuclear Group Limited is a wholly-owned subsidiary of British Nuclear Fuels Limited (BNFL) which itself is, in effect, publicly owned. The BNFL Board has recently announced its preference to pursue the sale of British Nuclear Group which they believe would be in the best interest of the company and its employees. This has raised many questions in West Cumbria and beyond as to what effect such a sell-off might have on the local supply chain, the long line of companies that supply British Nuclear Group either directly or via its sub-contractors. Before looking directly at that issue it is worth considering that such a sales process will take time to work through in any event. Also, the ultimate decision on any sale will be made by the BNFL Board after full consultation with stakeholders and, of course, the UK government through the Secretary of State for Trade and Industry. However, if we assume that British Nuclear Group is sold and/or another company takes over the decommissioning of Sellafield, what of the effects on the local supply chain? Well, regardless of the site operator, the work of decommissioning must and will go on, the NDA will see to that. Critically it will be managed in an open and competitive manner with all that means in exposing our local companies to the full effects of global competition. Many local companies will ruefully recognise the situation when I say that few favours are being offered them under the current structure as British Nuclear Group have been introducing procurement policies in line with European public sector guidelines. From this point of view, a change of corporate ownership may have little effect. Undoubtedly, however, a change would bring uncertainties and re-adjustment and it is likely that new players would enter the game. This is currently happening anyway as the huge opportunities offered by decommissioning are sought. What is important is that our local companies demonstrate their capability and competence to carry out the work effectively and efficiently. Local identity will not guarantee work irrespective of these issues but importantly, it will weigh favourably as a tie breaker. In other words, if all else is more or less equal in comparing bids for work, local identity will play an important part in the decision making. At this point it is worth mentioning that my own organisation, West Cumbria Development Agency, together with West Lakes Renaissance, is embarking on a 15-month project to assist our local companies to maximise the opportunities presented by nuclear decommissioning. This is the West Cumbria Supply Chain Project and it kicks off with a Meet the Buyer event at Sellafield on November 1 2005. Full details via Tracey Hyslop on 01900 65656 or tracey@wcda.co.uk ***************************************************************** 18 Guardian Unlimited Bush: Venezuela Nuke Reactor Might Be OK From the Associated Press [UP] Wednesday November 2, 2005 8:16 AM AP Photo MDEV104 By NEDRA PICKLER Associated Press Writer WASHINGTON (AP) - Despite tense relations with Venezuela, President Bush says it might be OK for the South American nation to have a nuclear reactor for peaceful energy uses. Bush acknowledged he had not heard about Venezuela's request for a reactor when asked about it Tuesday in an interview with Latin American reporters in advance of his five-day trip to the region. But he didn't reject the idea, even though he has had numerous disputes with Venezuelan President Hugo Chavez. As Chavez, Bush and leaders from 32 other nations in the Western Hemisphere prepare to gather Friday at the Summit of the Americans in Argentina, the Venezuelan leader is trying to boost his profile by putting his disputes with the United States at center stage. On Tuesday, Chavez said he would bring to the summit a message that the United States' ``capitalist, imperialist model'' was responsible for exploiting developing economies and ruining the global environment. He also warned he might share Venezuela's U.S.-made F-16 fighters with Cuba and China, accusing the United States of making it difficult for his country to obtain spare parts for the planes, which Venezuela originally purchased in 1983. Chavez has said his government was preparing for a possible U.S. invasion aimed at taking over Venezuela's oil fields, an allegation that U.S. officials have denied. He also has denounced the U.S.-led war in Iraq and said world leaders should consider moving the United Nations headquarters out of the United States. Chavez recently said he is interested in working with Iran to explore peaceful uses of nuclear energy. Chavez has insisted Iran has the right to develop nuclear energy despite opposition from the U.S. government, which fears Tehran may be developing a nuclear weapons program. Venezuela has asked for technical help from Argentina to develop nuclear energy. Bush said he would be curious to know what Argentine President Nestor Kirchner has to say about the idea. Kirchner and Chavez share left-leaning politics and have built close ties. Bush said he hopes Kirchner will agree with his position that international oversight of any nuclear development is important and noted that Venezuela already is an energy rich nation as one of the world's top oil producers. ``I guess if I were a taxpayer in Venezuela, I would wonder about the energy supply that Venezuela has,'' Bush said. ``But maybe it makes sense. I haven't really studied the proposal.'' Fred Jones, a spokesman for the National Security Council at the White House, later said that any nuclear cooperation with Venezuela would have to be in accordance with international obligations and safeguards set by the U.N. International Atomic Energy Agency. ``We have worked closely with Argentina to fight nonproliferation and look forward to continuing to do so in the future,'' Jones said. Bush's trip to Argentina, Brazil and Panama follows what has been one of the worst week's of his presidency. One of his top advisers was indicted, he had to replace his widely criticized Supreme Court nominee, and U.S. military deaths in Iraq passed the 2,000 mark. Bush even made light of the issue of reporter-source relationships that has been at the center of the investigation into who in his administration was responsible for leaking the name of a covert CIA operative to the media. The investigation led to Friday's perjury and obstruction of charges against I. Lewis ``Scooter'' Libby, Vice President Dick Cheney's chief of staff. When an Argentine reporter said sources told him that Kirchner planned to ask Bush for help reaching a new financial agreement on its debts with the International Monetary Fund, Bush expressed mock surprise that government officials can act as secret-leaking sources. ``I'm not going to ask you who they are, of course,'' Bush said, drawing laughter from the U.S. contingent in the room. ``Inside joke here, for my team.'' He went on to say that he would listen to any request that Kirchner makes in their private meeting, but the populist leader elected after Argentina's 2002 economic collapse appears ``plenty capable of dealing with the IMF directly'' without the United States as a ``middleman.'' The agenda at the Summit of the Americas centers on poverty reduction, with Bush promoting increased trade and the creation of other economic opportunities as the best solutions. But Bush acknowledged that he has been unable to accomplish what was once one of his highest trade priorities - the creation of a Free Trade Area of the Americas that remove tariffs and or barriers on all goods among every country in the Western Hemisphere except Cuba. The talks have been at an impasse for months, with co-chairs Brazil and the United States remaining far apart on a number of issues, including U.S. protections for American farmers and Brazil's laws covering the protection of intellectual property rights. --- On the Net: http://www.whitehouse.gov CIA World Factbook on Venezuela: http://www.cia.gov/cia/publications/factbook/geos/ve.html#Intro Guardian Unlimited © Guardian Newspapers Limited 2005 ***************************************************************** 19 NRC: NRC Proposes $3,250 Civil Penalty for N.J. Firm over Loss of Small Amount of Radioactive Material News Release - Region I - 2005-05 U.S. NUCLEAR REGULATORY COMMISSION Office of Public Affairs, Region I No. I-05-057 November 2, 2005 CONTACT: Diane Screnci (610) 337-5330 Neil A. Sheehan (610) 337-5331 E-mail: opa1@nrc.gov fine for a New Jersey analytical laboratory for the loss of a small sample of radioactive material earlier this year from its facility in Teaneck, N.J. The apparent violations for which the civil penalty has been proposed against Ledoux & Co. involve failures to adequately survey, secure and dispose of NRC-licensed material in accordance with the agencys requirements. Last March 30, the Ledoux laboratory in Teaneck received a shipment containing seven small analytical samples of uranium-235. A staff member opened the package on April 1, identified six of the seven samples, and performed an unsuccessful cursory search for the seventh sample. A more thorough search was conducted on April 12, resulting in the discovery that the shipping container had been removed as normal trash and a determination that the missing sample had been disposed of with the package. The NRC was notified of the apparent loss on April 13. In response, the agency began an inspection at the facility the next day. On May 11, Ledoux provided the NRC with a written report that concluded the package had been sent to a landfill and the sample was therefore unrecoverable. NRC concurred with the companys conclusion that it was not practical to try and retrieve the sample because (1) the material could have gone to a number of different landfills and (2) the material posed no threat to members of the public. Specifically, the sample involved emits less than one-tenth of a millirem per hour while the average member of the public receives about 360 millirems from manmade and natural sources each year. (A millirem is a measure of exposure to radioactivity.) After reviewing the event, the NRC has proposed the fine based on the following apparent violations: (1) staff at the Teaneck lab failed to adequately survey the package holding the samples and, because of this, one sample remained with the package; (2) even though a lab staff member could not account for all seven samples, no action was taken to retain the container, and when the package was removed from the facilitys restricted area and placed in a dumpster, the sample was no longer secured from unauthorized removal or access; and (3) the package was disposed of in a landfill. NRC considers the failure to secure and/or maintain control of radioactive material a serious matter. In this case, the failure . . . led to an improper transfer to an unauthorized recipient, NRC Region I Administrator Samuel J. Collins wrote in a letter to the company regarding the enforcement action. The company has 30 days to provide a written response to the enforcement action. Last revised Wednesday, November 02, 2005 ***************************************************************** 20 [DU Information List] MoD concedes that gulf war syndrome does Date: Wed, 02 Nov 2005 18:40:29 -0800 X-Spamprobe: ham-extreme * 0.0002134 OK 9999b.jpg My Groups | pandora-project Main Page MoD concedes that Gulf War syndrome does exist By Michael Evans, Defence Editor http://www.timesonline.co.uk/article/0,,2-1852147,00.html 999a5.jpg BRITISH soldiers who suffered debilitating illnesses after serving in the 1991 Gulf War were victims of a conflict-related syndrome, an appeals tribunal ruled yesterday. The landmark case involving the former Trooper Daniel Martin, 35, of the Life Guards, who is suffering from asthma, anxiety and memory loss, forced the Ministry of Defence to admit for the first time that the label of "Gulf War syndrome" was justified. The department's change of mind, contained in a judgment by the war pensions appeal tribunal in London yesterday, will have far-reaching implications. At least 1,500 other Gulf War veterans will now be able to claim a war pension. The veterans have blamed the illnesses on the cocktail of vaccines that they were given for protection against chemical and biological warfare. They also suspected that the organophosphate pesticides used to spray their tents to kill desert bugs may have contributed. The tribunal, in a reserved judgment, was critical of the MoD's previous refusal to accept the existence of Gulf War syndrome. The panel, which included a consultant psychiatrist and physician, said: "Fourteen years after the end of the Gulf War, the Veterans Agency (part of the MoD) has conceded the validity of the label GWS (Gulf War syndrome). "In that time many applications for such a condition were rejected, there have been numerous and expensive court cases and there are at present a number of ex-servicemen awaiting the result of this hearing. "It is not for this tribunal to ascertain why such a late concession was made, but the kindest comment that can be made is that the lateness of this concession was unfortunate." Former Trooper Martin, from Luton, said that he had fought for five years for a war pension on the basis that he was suffering from Gulf War syndrome. The MoD rejected his application because he "was determined to stick with that label". "I am delighted with the result. It will benefit all the other veterans suffering worse illnesses than me," he said. Mark McGhee, a lawyer with Linder Myers solicitors, in Manchester, who acted for Mr Martin, said that it was an "historic test case". Mr Martin served in Saudi Arabia, Kuwait and Iraq. Although the tribunal accepted that Gulf War syndrome was "the appropriate medical label", it said that Mr Martin had failed to produce reliable evidence to satisfy the burden of proof that Gulf War syndrome was "a discrete pathological entity". Last night the MoD welcomed this finding. Yahoo! Messenger NEW - crystal clear PC to PC calling worldwide with voicemail ---------- YAHOO! GROUPS LINKS * Visit your group "pandora-project" on the web. * * To unsubscribe from this group, send an email to: * pandora-project-unsubscribe@yahoogroups.com * * Your use of Yahoo! Groups is subject to the Yahoo! Terms of Service. ---------- Attachment Converted: 9999b.jpg: 00000001,21022f75,00000000,00000000 Attachment Converted: 999a5.jpg: 00000001,21022f76,00000000,00000000 ***************************************************************** 21 [du-list] MoD concedes that gulf war syndrome does exist Date: Wed, 02 Nov 2005 18:40:31 -0800 X-Temp-Whitesubject: YES du-list X-Spamprobe: ham-super * 0.0000157 OK MoD concedes that Gulf War syndrome does exist By Michael Evans, Defence Editor http://www.timesonline.co.uk/article/0,,2-1852147,00.htmlBRITISH soldiers who suffered debilitating illnesses after serving in the 1991 Gulf War were victims of a conflict-related syndrome, an appeals tribunal ruled yesterday. The landmark case involving the former Trooper Daniel Martin, 35, of the Life Guards, who is suffering from asthma, anxiety and memory loss, forced the Ministry of Defence to admit for the first time that the label of "Gulf War syndrome" was justified. NI_MPU('middle');The department's change of mind, contained in a judgment by the war pensions appeal tribunal in London yesterday, will have far-reaching implications. At least 1,500 other Gulf War veterans will now be able to claim a war pension. The veterans have blamed the illnesses on the cocktail of vaccines that they were given for protection against chemical and biological warfare. They also suspected that the organophosphate pesticides used to spray their tents to kill desert bugs may have contributed. The tribunal, in a reserved judgment, was critical of the MoD's previous refusal to accept the existence of Gulf War syndrome. The panel, which included a consultant psychiatrist and physician, said: "Fourteen years after the end of the Gulf War, the Veterans Agency (part of the MoD) has conceded the validity of the label GWS (Gulf War syndrome). "In that time many applications for such a condition were rejected, there have been numerous and expensive court cases and there are at present a number of ex-servicemen awaiting the result of this hearing. "It is not for this tribunal to ascertain why such a late concession was made, but the kindest comment that can be made is that the lateness of this concession was unfortunate." Former Trooper Martin, from Luton, said that he had fought for five years for a war pension on the basis that he was suffering from Gulf War syndrome. The MoD rejected his application because he "was determined to stick with that label". "I am delighted with the result. It will benefit all the other veterans suffering worse illnesses than me," he said. Mark McGhee, a lawyer with Linder Myers solicitors, in Manchester, who acted for Mr Martin, said that it was an "historic test case". Mr Martin served in Saudi Arabia, Kuwait and Iraq. Although the tribunal accepted that Gulf War syndrome was "the appropriate medical label", it said that Mr Martin had failed to produce reliable evidence to satisfy the burden of proof that Gulf War syndrome was "a discrete pathological entity". Last night the MoD welcomed this finding. --------------------------------- Yahoo! Messenger NEW - crystal clear PC to PC calling worldwide with voicemail [Non-text portions of this message have been removed] ------------------------ Yahoo! Groups Sponsor --------------------~--> Get fast access to your favorite Yahoo! Groups. Make Yahoo! your home page http://us.click.yahoo.com/dpRU5A/wUILAA/yQLSAA/FGYolB/TM --------------------------------------------------------------------~-> To unsubscribe from this groups send a message to du-list-unsubscribe@yahoogroups.com. In the body of the message type unsubscribe and send. ***************************************************************** 22 [DU-WATCH] Beyond Treason: Veterans exposure- Date: Wed, 2 Nov 2005 00:09:26 -0600 (CST) X-Fingerprint: owner-imap@chumbly.math.missouri.edu-127.127 Thanks for that info, Mark. Cheers, Elaine Thought for the day: If vegetarians eat vegetables, what do humanitarians eat? Mark Gailey wrote: http://www.beyondtreason.com/ Veterans (and Gulf region) exposure- Depleted Uranium Biological and Chemical warfare Experimental Vaccinations 110 minute DVD - free to military personnel and veterans 2 1/2 minute movie trailer - free .wmv download documented research on accompanying CD Mark Gailey http://www.libertyfelix.net/ SPONSORED LINKS U s government grant Berea kentucky hotel Berea kentucky Kentucky Berea kentucky real estate U s government student loan --------------------------------- YAHOO! GROUPS LINKS Visit your group "BereaPeace" on the web. To unsubscribe from this group, send an email to: BereaPeace-unsubscribe@yahoogroups.com Your use of Yahoo! Groups is subject to the Yahoo! Terms of Service. --------------------------------- [Non-text portions of this message have been removed] ------------------------ Yahoo! Groups Sponsor --------------------~--> Does he tell you he loves you when he hits you? Abuse. Narrated by Halle Berry. http://us.click.yahoo.com/CjRcdD/rbOLAA/xGEGAA/Sj.0lB/TM --------------------------------------------------------------------~-> [Brought to you by HTTP://WWW.STOPNATO.ORG.UK] ***************************************************************** 23 Xinhua: S.Korean truck loaded with missile parts blasts near Daegu www.xinhuanet.com www.chinaview.cn 2005-11-01 21:09:55 [A 15-ton truck reportedly loaded with parts of missiles blasted in a tunnel on an expressway near the South Korean city of Daegu on Tuesday.] SEOUL, Nov. 1 (Xinhuanet) -- A 15-ton truck reportedly loaded with parts of missiles blasted in a tunnel on an expressway near the South Korean city of Daegu on Tuesday. The blast occurred at around 2:18 p.m. (0518 GMT) in a tunnel on Guma Highway, which links Daegu city and Masan city, reported South Korean Yonhap News Agency. Daegu is some 300 kilometers southeast of Seoul. Fire fighters are trying to control the fire, said Yonhap. Witness was quoted by Yonhap as saying six or seven detonation were heard when the accidents occurred in the tunnel. At the time of the explosion, scores of vehicles were inside the tunnel. But there was not immediately report on casualties. Enditem Copyright ©2003 Xinhua News Agency. All rights reserved. ***************************************************************** 24 Sydney Morning Herald: BHP plans uranium mine upgrade - www.smh.com.au + Large font November 2, 2005 BHP Billiton expects growing global demand for nuclear power to ensure viability for a proposed $5 billion upgrade at its Olympic Dam copper-uranium mine. The project would see uranium production ramped up four-fold at the world's biggest uranium deposit, in South Australia, from 2013. Much of its success would depend on Australia's current negotiations on selling uranium to China - which is expected to quadruple China's nuclear energy production by 2020. But the project still faces massive hurdles with water, energy and transport demands expected to grow roughly in line with output at the remote desert site. The company is yet to make a final decision as it awaits the results of a $300 million pre-feasibility study due by the end of 2007. BHP Billiton base metals customer sector group vice-president Roger Higgins told a federal parliamentary inquiry he was confident of finding buyers for the projected output of 15,000 tonnes a year. The current figure is 4,000 tonnes a year. "Clearly energy demand is going to increase worldwide and I think everybody accepts that it will be substantial," Mr Higgins said. "All of the current energy sources are likely to increase along with that ... but what we anticipate is that uranium as a proportion is likely to increase. "We see a 60 per increase in all sorts of use over the next decade or so." However, spot prices for uranium of between $20 and $30 a pound exceeded the long-term contract price of $15 and were not expected to remain that high, he said. Nuclear power now generates 16 per cent of the world's electricity from 439 stations in 31 countries, with Australia accounting for 19 per cent of global uranium production - earning $475 million a year. But the industry has a poor public perception in Australia, despite recent urgings from Prime Minister John Howard for an informed debate on the merits of nuclear power. The federal government's renewed interest in the sector has sparked interest from 25 mining companies who have purchased exploration licenses in the Northern Territory. Dr Higgins said that with regards to nuclear power production, the 40 per cent market share now taken up by the de-commissioning of uranium from weapons was expected to slip to 17 per cent by 2020. Australia was in a good position to negotiate contracts for future uranium production due to its greater political stability than competitors in places such as Kazakhstan and parts of Africa, he said. Dr Higgins said while the company was interested in offshore exploration for uranium, it held no mining interests in other countries at this stage. At Olympic Dam, he said the company may look to build a 90km rail line from Woomera with the aid of federal government funding, and was also considering the merits of a gas line from Moomba for liquid fuel replacement. Environmental groups have been up in arms over a proposal to take five times as much water from the threatened Great Artesian Basin (GAB) to expand Olympic Dam. BHP Billiton spokesman Richard Yeeles told the inquiry the company was still considering its options, including a $300 million sea water desalination plant on Spencer Gulf. © 2005 AAP Copyright © 2005. The Sydney Morning Herald. National/Politics Updated Nov.2,2005 20:39 KST Local referendums at the potential locations for a radioactive waste dump wrapped up without a hitch in Pohang, Gyeongju and Yeongdeok in North Gyeongsang Province and Gunsan in North Jeolla Province on Wednesday evening, raising hopes that a project 20 years in the planning will finally get under way. The dump will be built in the location where it gets the most support. This is the first time a government project has been decided by plebiscite. The prime minister and the commerce, government administration and science ministers will meet to review the results of the referendum and discuss ways of supporting the winning site and pacify public sentiment in the other locations. The Ministry of Commerce, Industry and Energy said construction will start in the second half of 2007, to be completed by the end of 2008. (englishnews@chosun.com ) ***************************************************************** 27 INSIDE JoongAng Daily: [EDITORIALS] After the nuclear site vote November 3, 2005 KST 14:54 (GMT+9) The location of the nation's first permanent nuclear waste dump was decided in a vote yesterday by the residents of the candidate areas, although the winner was not yet known at press time late yesterday evening. This national project, which had been drifting for a long time, has finally been settled by directly asking the opinion of the site candidates' residents. Now there is one winner among the local governments of the four candidate sites ¡ª Gyeongju, Pohang and Yeongdeok in North Gyeongsang province and Gunsan in North Jeolla province ¡ª which had competed fiercely. All of them now should yield to the majority view. The campaigns against the nuclear dump have not been viciously waged this time, unlike past efforts of opponents of a dump. But there have been many allegations of illegal campaigning, and environmental groups have argued that the vote should be nullified. Some local governments have also incited their residents' antagonism against other regions. Now we have to minimize the problems in the aftermath of the vote. Environmental groups should stop stimulating conflicts between regions and residents. If the construction of a nuclear waste facility is stalled again, it would be a tremendous waste of national energy. The nation's 20 nuclear plants' temporary storage space for medium- and low-level nuclear waste will be filled in 2008. Over the last 19 years, the government has attempted to find a permanent nuclear waste dump site seven times, but failed each time. That was because the designated sites were based on unilateral decisions by the central and local governments, stimulating serious opposition from residents. That was clearly seen in Buan two years ago, where some residents resorted to violence to stop the waste site from opening there. But this time, residents of four candidate areas welcomed the vote and the regional development funds that the government offered. The incentives, including a 300-billion-won ($288-million) government subsidy, led the local governments of the candidate sites to campaign too energetically, giving room for complaints from the losers. Even the local government of the selected site will not be entirely happy because there will be conflicts with neighboring jurisdictions. There were a few problems in the voting, a rare procedure for this kind of decision. There was pressure by governments on voters, and there was a very large number of absentee ballots. Some changes are needed to curb intervention by government. 2005.11.02 Copyright by Joins.com, Inc. Terms of Use | ***************************************************************** 28 INSIDE JoongAng Daily: Nuclear waste ballot draws 60% turnout November 3, 2005 KST 14:54 (GMT+9) November 03, 2005 ¤Ñ Residents in four areas of Korea voted yesterday on how happy they would be with a nuclear waste dump in their backyards. Sixty percent of eligible voters in the four areas cast ballots, the National Election Commission said, although ballots were still being counted at press time last night. The local governments of the four areas ¡ª Gyeongju, Pohang and Yeongdeok in North Gyeongsang province and Gunsan in North Jeolla province ¡ª campaigned hard to increase support among residents, because the candidate site with the greatest majority of "yes" votes will get the nod and the largess that Seoul has promised to go along with the waste. Temporary storage sites at Korea's 20 nuclear reactor sites will be filled by 2008, so the site search is a pressing issue. Copyright by Joins.com, Inc. Terms of Use | ***************************************************************** 29 INSIDE JoongAng Daily: [VIEWPOINT] Citizens asked to make a choice November 3, 2005 KST 14:54 (GMT+9) Yesterday was a day when residents voted on whether to invite the construction of a nuclear waste disposal facility in their administrative districts. One of our country's long-term tasks, which has been embroiled in conflict for the past 19 years, may find a solution through the first experiment, a residents' referenda. Although Aomori prefecture in Japan decided to host a nuclear waste interim storage facility, there was no referendum, or citizens' vote, in Mutsu city in the prefecture, where the facility will be constructed. The decision on the construction of a nuclear dump, not a mere disposal facility for medium to low-level nuclear waste, was made through the approval of the local parliament alone, without a vote by the residents. Compared to Japan, we are following a high-level democratic procedure that respects the opinions of local residents. Thanks to their expectations of regional development accompanying the construction of the nuclear waste facility, the public's understanding of the facility has increased and a consensus has been reached between the concerned local autonomous governments and residents. Unlike the past, however, it is worrisome that overheated competition between the local governments to host the facility and residents who oppose the facility will bring adverse effects. The essence of the problem lies in the absentee vote. Requests for applications for absentee ballots from the four local governments that wish to host the facility, including Gyeongju and Pohang in North Gyeongsang province, Gunsan in North Jeolla province and Yeongdeok county in North Gyeongsang province, have turned out to be unprecedentedly high. Compared to the 2 to 3 percent rate in the past, the current application rates for absentee ballots were surprisingly high, with 38.1 percent in Gyeongju city, 39.4 percent in Gunsan, 27.5 percent in Yeongdeok county and 22.0 percent in Pohang city. The application rate for absentee ballots has increased because the requirements for absentee voting were greatly eased to promote residents' participation in the vote and special support was promised. Because of legislation to guarantee regional development with economic support, including a special grant of 300 billion won ($287 million), an annual fee of 8.5 billion won for hosting the facility, pursuit of combining a proton accelerator with the facility and the transfer of the main office of the Korea Hydro &Nuclear Co. to the locale, residents in the areas that applied for construction of the nuclear waste disposal facility have a greater expectation of local development than ever. Therefore, unlike in other elections held this year as well as in the past, the local residents who hope to host the facility were actively participating in the vote, taking relatively more interest in the issue. Seeing this move, some environmental groups and others that oppose the construction of the facility did not hesitate to call for nullifying the referendums, claiming that the votes are the result of corruption in which the central government and the local autonomous governments capitalized on the power of money and government power. Even in the legislative elections, not a few problems have occurred in the process of campaigns and elections. But the problems were solved through improvement of institutions and punishment of criminals, and elections themselves were never denied. As the referendum is not an established system yet, there could be many things that need to be improved, but the significance of the vote should not be undermined by putting the cart before the horse, as if the referendum itself had a problem. For a successful referendum, not only should the National Election Commission conduct a strict and thorough supervision of the voting process but also the local governments and residents should show a high level of political awareness so that the voting is fair and just. By instigating regional sentiment surrounding the construction of the nuclear waste disposal facility, they should not abuse the good intentions of the referendum that respects democratic procedure. Because the area with the highest approval rate will be selected as the construction site, the concerned local residents and autonomous governments should show a high level of grassroots democracy that readily yields to the results of the referendum with a spirit of fair play. If we fail to select the construction site for the nuclear waste disposal facility again this time as we are entangled in the controversy over the vote, not only will the local governments suffer damage but the country will also lose its honor and all the people will end up carrying the burden. Therefore, the National Election Commission, the government and each local government should supervise the referendums more thoroughly to prevent the occurrence of controversy over the results of the votes. Also, the local residents of the areas concerned should use greater prudence in the matter, so that the problem of constructing the nuclear waste disposal facility that has been adrift for 19 years is resolved this time. I sincerely expect that the referendum will remain an exemplary precedent in which a conflicting policy issue is resolved democratically. * The writer is a professor of international politics at Hanyang University. Translation by the JoongAng Daily staff. by Kim Kyung-min 2005.11.02 Copyright by Joins.com, Inc. Terms of Use | ***************************************************************** 30 Salt Lake Tribune: Dumping can be avoided Opinion Article Last Updated: 11/01/2005 10:58:39 PM I believe that the dumping of radioactive soil near the San Juan River can be avoided by creating facilities that can recycle nuclear waste. They may not exist yet but it would be a good idea. But what's worse is that the government is putting Japanese radioactive waste in a beautiful desert that is near people. The radioactive soil could harm the humans in and near Blanding. One of the hardest parts to accept about the dumping is that there are a lot of wonderful animals in the area. The soil could harm the human and animal populations of Utah, Colorado and New Mexico. Aren't there risks to depositing the soils? Please don't turn our beautiful state into a nuclear dump zone. Sophie Bona-Layton Salt Lake City © Copyright 2005, The Salt Lake Tribune. ***************************************************************** 31 Xinhua: Ukraine denies burying nuclear waste near Russian border www.xinhuanet.com www.chinaview.cn 2005-11-02 13:03:08 KIEV, Nov. 1 (Xinhuanet) -- Ukrainian Foreign Minister Boris Tarasyuk on Tuesday refuted a media report that Ukraine had allegedly buried chemical and nuclear waste near its border with Russia. Evidence from defense, emergencies and nuclear authorities showed that the report by the Komsomolskaya Pravda, an electronic periodical, regarding the chemical and nuclear waste burial had been untrue and irresponsible, Tarasyuk said at a press conference. Komsomolskaya Pravda recently published an article saying that Ukraine had allegedly buried chemical and nuclear waste near the Ukrainian-Russian border. Tarasyuk said Ukraine, as a signatory country of the Convention on the Banning of Chemical Weapons and a member of the Hague-based Organization for the Prohibition of Chemical Weapons (OPCW), had passed five checks by the OPCW without any violation. The minister also denied the allegation that Ukraine had buried nuclear waste, noting that the country's nuclear facilities and treatment of nuclear waste had been closely monitored by the International Atomic Energy Agency. Enditem Copyright ©2003 Xinhua News Agency. All rights reserved. ***************************************************************** 32 Globe and Mail: Chiefs warn of nuclear waste plans for native territory Some are worried at possible moves to bury spent fuel in the Canadian Shield By BILL CURRY Wednesday, November 2, 2005 Posted at 5:39 AM EST From Wednesday's Globe and Mail Regina — Aboriginal chiefs gathered from across the country are being put on notice that plans are afoot to bury nuclear waste in their traditional territory. Outside the Regina convention room where more than 600 chiefs of the Assembly of First Nations are gathered this week, the AFN has set up a large display, complete with pictures, of how nuclear waste could be buried inside the Canadian Shield in the coming decades. "Yikes," said one woman at the convention as she scanned the display outlining the AFN's "Nuclear Waste Dialogue." David Gorman, one of the AFN's four co-ordinators for the dialogue, has been visiting reserves to let chiefs and tribal council members know that key decisions are being made about storing nuclear waste that could affect native reserves in the coming decades. "I'll talk about radiation and a little bit of the science. I'll talk about the proposed options for economic opportunities for regions," Mr. Gorman said, in describing his presentations. "I would just say, 'Be aware that industry might approach [your community] to build a facility on your territory and they might sweeten the deal with economic opportunities and money.' " The issue is being driven by the impact of the federal Nuclear Fuel Waste Act, passed by Parliament in 2002. The law created a new Nuclear Waste Management Organization, led by representatives of Canada's nuclear industry. The organization is scheduled to report in two weeks on its long-term plan for storing nuclear waste. Mr. Gorman said earlier reports from the organization suggest it will likely propose that the current system of storing waste at the site of nuclear reactors should be continued for the next 60 years, after which deep storage facilities in the Canadian Shield should be ready for use. The Canadian Shield is the deep rock bed that lies underneath most of Quebec and Northern Ontario. Parts of Saskatchewan are also being considered as potential locations for nuclear deep storage. The AFN's nuclear dialogue is being paid for with money from the nuclear organization and Natural Resources Canada. Mr. Gorman would not say how much money the AFN received from the nuclear organization, but the AFN's own summary report of its dialogue reveals the funding arrangement doesn't sit well with some. "Some participants expressed discomfort at the idea that the AFN was there to promote the [nuclear organization's] objectives and obtain 'buy in' to the current process," says the summary report from the AFN to Elizabeth Dowdeswell, the nuclear organization's president. John Beaucage, the grand council chief for the Union of Ontario Indians, which represents several native reserves on the Canadian Shield, said he would advise any community not to store nuclear waste on its territory. Mr. Beaucage said promises of large amounts of money may be enticing for poorer communities, but the long-term impact should be considered. "It might look good in the short term but when you're talking about nuclear waste, there's no such thing as short-term," he said. "It's just a very, very scary thought." While reserves are relatively small and it would be highly unlikely that such facilities would be built on reserve land, each aboriginal community considers the broader surrounding area to be part of its "traditional territory," which may also be specifically defined by treaties. Such land is also owned by the Crown, creating the possibility that such facilities could be built against the wishes of the closest reserve. Mr. Gorman said that, so far, no community has volunteered to work with the nuclear industry. He said his presentation is normally met with "a sense of shock" given there is little knowledge of nuclear-waste issues or that a plan is in the works that could involve traditional lands. The debate comes as the Ontario government has signalled it will become more dependent on nuclear energy as it phases out coal power. As chiefs wandered by the AFN display, Mr. Gorman said he has been told of many negative experiences that reserves have had with the uranium-mining industry. One aboriginal community in the Northwest Territories, for example, used to be referred to as the Village of Widows after most of the men in the area died because they were hired to carry uranium from a local mine without any protection. Latest Comments in the Conversation Editor's Note: Globeandmail.com editors read and approve each comment. Comments are checked for content only, spelling and grammar errors are not corrected and comments that include vulgar language or libelous content are rejected. 1.brian smythe from moose jaw, Canada writes: It seems that the Indian Reserves are about to become a very big issue in the coming future. We are seeing the present problems that are on the reserves with the water problems that have come to light. The goverment and the companies involved in the setup of these nuclear storage plants will buy out the natives ,to put the plantswhere they want, but at the same time they will forget to properly educate and inform the natives of what the future problems will be till it is to late. I find a large number of people who feel that the natives along with the immigrants to Canada are being given a free ride. They see nothing but money given from the taxes they pay given away . Our goverment has missed the boat again , handouts do not help anyone better themselves.The native groups are in trouble and a very large part is their own doing , not to say that they are the only ones to blame . + Posted Nov. 2, 2005 at 12:04 PM EST + 2.Denise Billy from West Vancouver, Canada writes: This is ridiculous. What an outrage! How irresponsible!. Now if this were to happen in B.C. I am quite sure thatthis nuclear waste could very well be put on Capilano Reserve or Mission Reserve. Capilano reserve has the dump AND railroad trucks running through it. I am so fed up with our government dumping waste, building railroad tracks, and locating reserves right beside the highways here in B.C. Now my first nations people are having nuclear waste being dumped on traditional territory?It is high time for AFN to stop thinking money and taking"handouts" the government keeps stuffing down our throats and MAN UP! Say No! We as a Fist Nations community must learn to be self efficient without the government handouts where we as native people are getting the low end of the deal!!! Do you really think the nuclear waste dump would be located in the posh side of Regina? No........go dump it on native traditional territory!! Or if it were to happen here do you think it would be convenientlydumped in the British Properties? I highly doubt that! postamble(); + Posted Nov. 2, 2005 at 12:18 PM EST + 3.Stu S from Ottawa, Canada writes: I must say that I am tired of people over reacting to things they don't understand. Nuclear material comes from the earth in the first place. Putting it back where we found it when we are done with it just makes sense. And as Canadian we actually have a lot of expertise in regards to nuclear fuel. Nearly a third of the world's supply of uranium comes from northern Saskatchewan! Deep burial is quite safe especially in this country where we have strict government regulations on the nuclear industry. + Posted Nov. 2, 2005 at 12:28 PM EST + 4.Mark Outhwaite from Toronto, Canada writes: Europeans appropriated this land using violence,then some time later,successive generations propose inserting highly radioactive substances into vast repositories underground. First Nations lived in harmony with nature for tens of thousands of years,a duration of time that coincides with the half-life of certain forms of radioactive nuclear waste. A way of living that places the human being in harmony with their environment is subverted by sweeping the radioactive embers of industrial civilization under their rug,not ours. An subscriber + Posted Nov. 2, 2005 at 1:00 PM EST + 5.Douglas Cochrane from Dartmouth, Canada writes: It is shameful that in the 21st. Century we still feel that we can by off the natives with a few trinkets and empty promises.Yes we do need to find a place to store nuclear waste but why does it have to be on native soil.Our aboriginal people have given up a lot since we arrived in the new world, we have reduced their numbers through our diseases, killed thousands outright, and sent the rest into exile on reserves.We have polluted, stripped, and permanently altered the pristine land that was once theirs and now we want to use whats left as a dump.I hope those that are paid to make the "big" decisions look a little harder at finding a better place to store nuclear waste.A closed military base perhaps? Douglas Cochrane Dartmouth, NS. + Posted Nov. 2, 2005 at 2:36 PM EST Globeandmail.com: ***************************************************************** 33 Review: Individuals respond to perchlorate differently Foodconsumer.org Last Updated: Nov 2nd, 2005 - 08:23:35 Genetic Factors That Might Lead to Different Responses in Individuals Exposed to Perchlorate Franco Scinicariello, H. Edward Murray, Lester Smith, Sharon Wilbur, and Bruce A. Fowler Division of Toxicology, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Georgia, USA * Introduction * Public Health and Perchlorate * Mode of Action of Perchlorate in Humans * Thyroid Hormone Synthesis * Relevant Studies of Perchlorate in Humans * Conclusions Abstract Perchlorate has been detected in groundwater in many parts of the United States, and recent detection in vegetable and dairy food products indicates that contamination by perchlorate is more widespread than previously thought. Perchlorate is a competitive inhibitor of the sodium iodide symporter, the thyroid cell-surface protein responsible for transporting iodide from the plasma into the thyroid. An estimated 4.3% of the U.S. population is subclinically hypothyroid, and 6.9% of pregnant women may have low iodine intake. Congenital hypothyroidism affects 1 in 3,000 to 1 in 4,000 infants, and 15% of these cases have been attributed to genetic defects. Our objective in this review is to identify genetic biomarkers that would help define subpopulations sensitive to environmental perchlorate exposure. We review the literature to identify genetic defects involved in the iodination process of the thyroid hormone synthesis, particularly defects in iodide transport from circulation into the thyroid cell, defects in iodide transport from the thyroid cell to the follicular lumen (Pendred syndrome), and defects of iodide organification. Furthermore, we summarize relevant studies of perchlorate in humans. Because of perchlorate inhibition of iodide uptake, it is biologically plausible that chronic ingestion of perchlorate through contaminated sources may cause some degree of iodine discharge in populations that are genetically susceptible to defects in the iodination process of the thyroid hormone synthesis, thus deteriorating their conditions. We conclude that future studies linking human disease and environmental perchlorate exposure should consider the genetic makeup of the participants, actual perchlorate exposure levels, and individual iodine intake/excretion levels. Key words: genetic susceptibility, hypothyroidism, mutations, NIS, Pendred syndrome, pendrin, perchlorate, thyroid gland, TPO. Environ Health Perspect 113:1479-1484 (2005). doi:10.1289/ehp.8076 available via http://dx.doi.org/ [Online 29 June 200] Introduction Sequencing of the human genome has brought new emphasis and increased interest in gene-environment interactions and is becoming relevant in defining public health policies. For many years, people's susceptibility to xenobiotics have been known to differ significantly. Now, several techniques are available to identify and characterize the genetic correlates of interindividual variability. The goal of environmental genomics is to help investigators understand how genetic variability influences individual responses to environmental factors on the basis of the assumption that high-risk genotypes accumulate more damage and therefore are at greater risk of developing exposure-related diseases. Thus, genomics information may lead to development of predictive biomarkers that identify potentially sensitive populations and earlier prediction of adverse outcomes, ultimately resulting in better intervention strategies (Kelada et al. 2003). Public Health and Perchlorate The advent and use of new, highly sensitive detection techniques have identified contamination of groundwater by perchlorate in many parts of the United States, primarily in association with industries involved in rocket, explosives, and fireworks manufacturing and propellant handling. Concentrations measured in most public water supplies are 90%), virtually unchanged (Anbar et al. 1959; Eichler and Hackenthal 1962). Several other inorganic anions such as thiocyanate and nitrate that are present in dietary and environmental sources have goitrogenic effects (Greer et al. 1966). Similar to perchlorate, they both competitively inhibit iodide uptake at NIS. Several studies have been conducted to determine the relative effects of perchlorate, thiocyanate, and nitrate on radioactive iodine uptake (RAIU) inhibition. Studies in rats showed that perchlorate was approximately 10 times more potent than thiocyanate and about 300 times more potent than nitrate in inhibiting RAIU in the thyroid. Furthermore, thiocyanate was slightly more potent than iodide (Wyngaarden et al. 1953). Tonacchera et al. (2004) demonstrated, in Chinese hamster ovary (CHO) cell lines stably transfected with the human NIS gene, that the relative potency of perchlorate on RAIU inhibition was 15, 30, and 240 times that of thiocyanate, iodide, and nitrate, respectively. The inhibiting effects when the cell lines where exposed to a mixture of perchlorate, thiocyanate, and nitrate were simply additive. Thyroid Hormone Synthesis Thyroid hormone plays a key role in the growth and differentiation of many organs. It is especially important for development of the central nervous system during the prenatal and postnatal periods (reviewed by Zoeller et al. 2002). A severe shortage of TH for several weeks after birth results in serious mental and motor handicaps. During pregnancy the mother provides substantial amounts of TH to the fetus (Vulsma et al. 1989), so the delay in cerebral development caused by congenital hypothyroidism (CH) results mainly from postnatal TH deficiency. The risk for mental retardation and the difficulty in recognizing the disease were reasons for introducing neonatal mass screening programs. Therefore, the most serious effects of perchlorate might occur during the first trimester when the brain is forming and developing and TH supply is totally dependent on maternal supply of iodine and of thyroxine (T4) and triiodothyronine (T3) To understand the potential impact of perchlorate on a gene-environment interaction model, we need to consider T3 and T4 in a proper biosynthesis context. TH synthesis and secretion are exquisitely regulated negative-feedback systems that involve the hypothalamus, pituitary, and thyroid glands. The hypothalamus secretes thyrotropin-releasing hormone (TRH), a tripeptide (pyroGlu-His-Pro) synthesized in the paraventricular nucleus of the hypothalamus. The TRH, transported by axons, binds to TRH receptors in the pituitary thyrotropes, a subpopulation of pituitary cells that secrete thyroid-stimulating hormone (TSH). TRH stimulation leads to release and synthesis of new TSH in thyrotropes. The TSH binds to the TSH receptor in the thyroid gland cells. TSH is the primary regulator of TH release and secretion. Both TRH and TSH secretion are negatively regulated by THs: when T4 reaches an adequate circulating level, the hypothalamus and pituitary reduce their output of TRH and TSH; they increase their output of TRH and TSH when the circulating blood level of T4 is low. A number of thyroid genes, including NIS, thyroglobulin (Tg), and thyroid peroxidase (TPO), are stimulated by TSH and promote the synthesis of TH (Zoeller 2003). Iodine is critical to thyroid gland function and TH synthesis and secretion. The first step in thyroidal iodine metabolism is the cellular uptake of iodide from the extracellular fluid. The thyroidal iodine uptake is tightly regulated by the NIS, an intrinsic plasma membrane protein in the thyroid follicular cells (Dohán et al. 2003). From the follicular cell, the iodide moves across the apical membrane, transported by pendrin protein (Yoshida et al. 2002). The iodide is then delivered to the cell-colloid interface, where it is oxidized by TPO and bound to tyrosyl residues in the Tg. This iodination of specific tyrosines on Tg yields monoiodinated and diiodinated residues [monoiodotyrosines (MITs) and diiodotyrosines (DITs)] that are enzymatically coupled to form T4 and T3. The iodinated Tg containing MIT, DIT, T4, and T3 then is stored as an extracellular storage polypeptide in the colloid within the lumen of thyroid follicular cells. Perchlorate does not undergo metabolism, but genetic defects of its target, that is, the NIS, may lead to low iodine uptake in the thyroid gland, thus depressing production of THs. In this scenario, exposure to perchlorate may further reduce the already low iodide uptake and decrease production of THs. The combined effects of perchlorate with a genetic decrease in THs would hence delineate a population at risk for decreased thyroid function. We reviewed published data to identify genetic factors that might lead to different responses in people exposed to perchlorate in the environment. Because perchlorate inhibits iodide uptake, we focused on the genetic defects causing CH involving the iodination process of the THs, particularly a) defects in iodide transport from circulation into the thyroid cell; b) defects in iodide transport from the thyroid cell to the follicular lumen, often combined with inner ear deafness [Pendred syndrome (PDS)]; and c) defects of iodide organification. A positive perchlorate discharge test is used as a diagnostic tool in most of these medical conditions. A positive diagnosis can be obtained by administering 1 g potassium perchlorate 2 hr after a tracer dose of 131I. In normal individuals, radioiodide accumulation in the thyroid gland ends after the administration of potassium perchlorate, but there is little loss of the thyroidal radioactivity previously accumulated in the gland. Instead, potassium perchlorate causes almost complete discharge of the unbound fraction of thyroid iodide in individuals with defects of iodide organification and with PDS. Therefore, these people could have different responses to environmental perchlorate exposure than normal individuals. Defects in iodide transport from circulation into the thyroid cell. The NIS is the plasma membrane glycoprotein that mediates active iodide uptake into the thyroid follicular cells. This process is the crucial first step in TH biosynthesis. NIS couples the inward transport of sodium, which occurs in favor of its electrochemical gradient, to the simultaneous inward translocation of iodide against its electrochemical gradient. Two sodium ions per iodide ion are translocated into the cells (Dai et al. 1996; Eskandari et al. 1997). The sodium gradient that drives iodide uptake is maintained by the Na+/K+ ATPase. Congenital iodide transport deficit (ITD) is an infrequent autosomic recessive condition characterized by inability of the thyroid gland to maintain a concentration gradient of iodide between the plasma and the thyroid follicular cell, resulting in hypothyroidism, diffuse or nodular goiter, and little or no uptake of radioiodine. The disorder has been linked to a defect of the NIS. In the absence of a functional NIS molecule, iodide has no access to the thyroid follicular cells, resulting in decreased TH biosynthesis and higher circulating levels of TSH, which in turn stimulates the morphologic and biochemical changes in the thyroid that result in development of goiter (De La Vieja et al. 2000). The gene coding for human NIS has been mapped to chromosome 9p12-13.2. It has 15 exons and coding for a glycoprotein of 643 amino acids. NIS is a protein with 13 putative transmembrane domains, an extracellular amino terminus, and an intracellular carboxyl terminus (De La Vieja et al. 2000). About 58 cases of ITD from 33 families have been reported worldwide. Thirty of 31 cases from 21 families were studied at the molecular level and had several homozygous or compound heterozygous mutations of the perchlorate-sensitive NIS gene. Eleven mutations have been identified: V59E, G93R, Q267E, C272X, T354P, G395R, frameshift 515X, Y531X, G543E, uc DeltaM142-Q323, and uc DeltaA439-P443 (Fujiwara et al. 1997, 1998, 2000; Kosugi et al. 1998a, 1998b, 1999, 2002; Matsuda and Kosugi 1997; Pohlenz et al. 1997, 1998; Tonacchera et al. 2003). The single substitution in codon 354 converting from ACA (Thr) to CCA (Pro) was the most common mutation detected in 10 patients with homozygous mutations, and in four patients with compound heterozygous mutation (Fujiwara et al. 1997, 1998; Kosugi et al. 1998a, 1998b; Matsuda and Kosugi 1997). All were Japanese, suggesting that the mutant NIS T354P is more common in Japan. However, the frequency of this gene in the Japanese population is unknown because only 185 healthy people, representing only 370 alleles, have been genotyped. The frequency of mutations in the NIS gene in the population is not known. Heterozygous persons do not express the phenotype; therefore, NIS gene defects can be detected only when both alleles are affected. People with homozygous mutations that cause partial loss of function may not be detected when, under conditions of high iodide intake, full preservation of iodide concentrating function is not required to achieve normal hormone synthesis. Therefore, impairment of thyroidal iodide concentration requires not only mutations in both NIS alleles but also defects that cause virtually complete loss of function. The therapeutic treatment of ITD patients consists of l-T4 administration. Some patients also are supplemented with potassium iodide, thus underscoring the degree of functional loss of the mutated NIS. In these persons, perchlorate intake from contaminated sources could further reduce the functional activity of the mutated NIS in concentrating iodide in the thyroid. Defects in iodide transport from the thyroid cell to the follicular lumen, often combined with inner ear deafness (PDS). PDS, an autosomal recessive disorder characterized by deafness and goiter, is the most common cause of syndromic deafness, accounting for up to 10% of all hereditary hearing loss (Fraser 1965; Nilsson et al. 1964). A phenotypic heterogeneity exists among affected persons, and thyroid dysfunction is particularly variable. At least 50% of affected persons have normal circulating levels of TH, whereas others develop clinical hypothyroidism (Reardon et al. 1999). Most affected persons demonstrate impaired iodide organification, as determined by a positive perchlorate discharge test. Hearing loss in PDS is prelingual and, in at least 80% of patients, is associated with structural defects of the inner ear, including a dilatation of the vestibular aqueduct and the Mondini defect of the cochlea (Johnsen et al. 1989). The PDS gene (SLC26A4) has been linked to chromosomal region 7q31 and contains an open reading frame of 2,343 bp encompassing 21 exons (Coyle et al. 1996; Sheffield et al. 1996). The predicted gene product pendrin is a highly hydrophobic 780 amino acid protein that transports chloride and iodide and mediates the exchange of chloride and formate. In the thyroid gland, a disorder in the function of pendrin may cause diminished iodide transport over the apical membrane that results in iodide remaining in the thyrocyte and a consequent decrease of organification of iodide. As a result, iodide accumulates in the cytoplasm and is discharged if thiocyanate or perchlorate is given (perchlorate discharge test). A decrease in the amount of radiolabeled iodide over the thyroid of > 10% is considered positive. At least 85 independent SLC26A4 gene mutations have been characterized as causing PDS and nonsyndromic deafness, in some cases confirmed by a normal perchlorate discharge test (Adato et al. 2000; Blons et al. 2004; Bogazzi et al. 2000, 2004; Campbell et al. 2001; Coucke et al. 1999; Coyle et al. 1998; Everett et al. 1997; Fugazzola et al. 2000; Kopp et al. 1999; Li et al. 1998; Lopez-Bigas et al. 2002; Namba et al. 2001; Park et al. 2003; Prasad et al. 2004; Reardon et al. 2000; Scott et al. 2000; Tekin et al. 2003; Tsukamoto et al. 2003; Usami et al. 1999; Van Hauwe et al. 1998; Yong et al. 2001). Although these mutations are distributed throughout the coding sequence, having been identified in 19 of the 21 exons, the spectrum of mutations appears to show geographic differences. In Caucasian patients, the L236P, T416P, and IVS8+1G > A mutations account for nearly half of all SLC26A4 mutant alleles, whereas in Japanese patients, these mutations are rare (Campbell et al. 2001; Tsukamoto et al. 2003). By contrast, H723R and ISV7-2A > G are the prevalent alleles accounting for most observed SLC26A4 mutations in Korean and Japanese studies (Park et al. 2003; Tsukamoto et al. 2003). Some researchers have suggested that the frequency of these mutations could represent a founder effect rather than mutational hot spots. A disorder in the function of pendrin will cause a diminished iodide transport over the apical membrane, which causes iodide to remain in the thyrocyte. Intake of perchlorate from a contaminated source may cause discharge of iodide from the thyrocyte, further exacerbating the organification defect, with resulting decrease of TH synthesis. Moreover, at present, it is not known whether perchlorate will affect the function of the normal pendrin protein to transport iodide. Molecular studies addressing whether perchlorate may act on iodide transport through inhibition of the pendrin protein in a fashion similar to the NIS are needed and welcomed. Defects in iodide organification. Iodide organification is the process by which iodine is oxidized and bound to thyrosine residue in Tg. Thyroid iodide organification disorder represents a group of defects characterized by discharge of substantial percentage of labeled iodide from the thyroid after administration of perchlorate (perchlorate discharge test) or thiocyanate. This discharge indicates a defect in converting accumulated iodide to organically bound iodine. The discharge may be partial or complete, thus defining partial or total defects. Partial iodide organification defects (PIODs) are characterized by release of 90% of the accumulated radioiodine. Iodination of the tyrosine residue is catalyzed by the membrane-bound thyroperoxidase (TPO). However, the oxidation of iodine requires hydrogen peroxide synthesized outside the thyroid follicular cell at the apical border catalyzed by the thyroid complex. Recently, two proteins of this complex, DUOX1 (also known as THOX1) and DUOX2 (also known as THOX2), have been identified (De Deken et al. 2000; Dupuy et al. 1999). The DUOX1 and DUOX2 genes are co-localized on the 15q15.3 chromosome and code for proteins of 1,551 and 1,548 amino acids, respectively. The DUOX1 and DUOX2 structure includes seven transmembrane-spanning domains, three NADPH- and one FAD-binding site, and 2EF-hand motifs. During the past three decades, few cases of thyroidal hydrogen peroxide have been described, but the molecular bases of these defects have just recently been investigated. Moreno et al. (2002) reported mutations in the DUOX2 gene, resulting in premature stop codon, in four CH patients with unexplained iodide organification defects. One patient with permanent CH and TIOD carried a homozygous substitution, whereas three patients with temporary CH and PIOD carried heterozygous mutations that cause premature termination signal. Lack of or insufficient activity of the DUOX2 protein diminishes hydrogen peroxide production, resulting in decreased activity of TPO and accumulation of iodide in the thyrocyte. Intake of environmental perchlorate, which inhibits iodine inflow, also may cause discharge of unbound iodine, further deteriorating the iodine organification process. Under oxidative conditions, TPO catalyzes the coupling of iodotyrosines to iodothyronine residue in Tg. Thyroperoxidase is a glycosylated hemoprotein encoded by the TPO gene located on chromosome 2p25. The gene contains 17 exons coding for a protein of 933 amino acids. The protein has a transmembrane helix with a large extracellular N-terminal part containing a heme group. TPO defects are believed to be among the most frequent causes of abnormalities in thyroid iodide organification defect causing goitrous CH. TPO activity is not detectable in thyroid tissue of patients with TIOD. Absence of TPO activity implicates the inability to iodinate tyrosine residue in Tg and to couple these residues to form THs, mainly T4 and some T3 and rT3 (reverse T3) Inactivating mutations in both TPO alleles have been found in patients with CH caused by TIOD. With use of a variety of molecular techniques for mutation deletion, 36 mutations have now been defined for TPO. These include frameshift mutations caused by nucleotide insertion or deletion, as well as missense, nonsense, and splice site mutations (Abramowicz et al. 1992; Ambrugger et al. 2001; Bakker et al. 2000; Bikker et al. 1994, 1995, 1997; Kotani et al. 2001; Nascimento et al. 2003; Niu et al. 2002; Pannain et al. 1999; Rivolta et al. 2003; Santos et al. 1999; Umeki et al. 2002, 2004; Wu et al. 2002). The first reported mutation was a homozygous GGCC insertion in exon 8 of the TPO gene. The resulting frameshift generates a stop codon in exon 9, which results in a grossly truncated protein with no expected activity (Abramowicz et al. 1992). In a Dutch study of 45 patients from 40 families with CH caused by TIOD, the GGCC insertion in exon 8 at nucleotide position 1287 was the most common mutation found (Bakker et al. 2000). It was detected in 36% of the investigated TPO alleles and in 51% of the families investigated either in a homozygous or a compound heterozygous fashion. In this study, mutations in both TPO alleles were found in 29 families: for 13 families in a homozygous fashion and for 16 families in a compound heterozygous fashion. A total of 16 different mutations were found, including 8 novel mutations: 6 frameshift mutations, 6 missense mutations, 3 splice site mutations, and 1 nonsense mutation. Most of these mutations occurred in exon 8, 9, or 10, which encode for the active part of the enzyme involved in the heme binding. In one patient with classic TIOD, a homozygous deletion in exon 14 appeared to have resulted from partial maternal isodisomy of the short arm of chromosome 2 carrying the defective TPO gene (Bakker et al. 2001). In some patients alternative splicing would generate a partially active form of the enzyme. In others an early termination signal would prevent translation of the fully active protein (Abramowicz et al. 1992; Bikker et al. 1994, 1995; Mangklabruks et al. 1991; Santos et al. 1999). Umeki et al. (2002) described 2 novel mutations in the TPO gene, R665W and G771R, in exons 11 and 13, respectively. The former was found in the patient's father (heterozygous) and the latter in her mother, also heterozygous. No TPO activity was detectable with cells transfected with mutated mRNAs. Moreover, the mutated TPO proteins showed abnormal cellular localization, exhibiting immunofluorescence only in the intracellular structure. Therefore, the loss of apical membrane localization of the mutated TPO was the main cause for the iodide organification defect. PIODs also can be caused by disorders in TPO. In an investigation of TPO mutations in five families with PIOD, Nascimento et al. (2003) found a compound heterozygous mutation in three patients from one family inherited from both heterozygous parents. In the other four families, they found only heterozygous TPO mutations or polymorphisms, suggesting the translated protein could be partially inactive. Recently, PIOD caused by TPO gene was diagnosed in three siblings (Kotani et al. 2003). The three siblings with goiter and latent-to-mild hypothyroidism had a compound heterozygous mutation for a missense mutation (G1687T) and a deletion in exon 10 (1808-13del), resulting in a produced protein with two deleted amino acids uc DeltaD574-L4575. From the expression studies, the mutated uc DeltaD574-L4575-TPO synthesized THs to some extent (Kotani et al. 2003). A common feature of patients with thyroid organification disorders syndrome is the discharge of iodine from the thyroid after administration of perchlorate. The level of perchlorate administrated in the diagnostic test is higher than the reported level of contaminated sources. However, it is biologically plausible that cumulative ingestion of perchlorate through a contaminated source may cause some degree of iodine discharge from thyrocytes. In populations with partial activity of the TPO enzyme, exposure to high enough levels of environmental perchlorate could cause unbound iodide discharge; therefore, less iodine will be available for biosynthesis of THs, thus further deteriorating their conditions. Relevant Studies of Perchlorate in Humans Many studies have attempted to provide useful information on the dose-response relation of perchlorate-related health effects. Several ecologic studies have compared thyroid function in newborns using T4 and TSH screening data in infants born to mothers in areas with different perchlorate exposure. However, these studies yielded contradictory results. Brechner et al. (2000) found higher TSH in newborns in Yuma, Arizona, which has high perchlorate exposure, than in Flagstaff, Arizona, which has lower exposure. However, whether perchlorate exposure caused the observed TSH effect cannot be addressed because of the lack of direct perchlorate measurement in the study. By contrast, F.X. Li et al. (2000) and Z. Li et al. (2000) found no association in Nevada newborns between low T4 and TSH levels and perchlorate exposure. A limitation of these studies is that the investigators did not collect data on individual exposure to perchlorate and on iodine intake levels. In a population-based ecologic study using California Newborn Screening Program data, Schwartz (2001) claimed to identify a significant dose-response association between perchlorate exposure and T4, and an association of perchlorate exposure and being a presumptive positive for CH. These data contrast with a previous ecologic analysis (Lamm and Doemland 1999) that found no increase of CH incidence in California and Nevada counties with perchlorate levels of 4-16 µg/L in drinking water supplies. Crump et al. (2000) conducted a study in three proximate cities in northern Chile that had different concentrations of perchlorate in tap water, involving 162 school-age children and 9,784 newborns. These authors found no alteration of thyroid function or incidence of CH in Taltal, Chile, where the tap water contained 100-120 µg/L perchlorate, compared with two other regions of Chile with low or no perchlorate in the water. However, the data also showed high levels of urine iodine, indicating that iodine intake in the population was very high, possibly overcoming the inhibitory effect of perchlorate on thyroid function. To establish the dose response in humans for the perchlorate inhibition of thyroidal iodide uptake and the short-term effects on circulating TH, Greer et al. (2002) gave perchlorate in drinking water at 0.007, 0.02, 0.1, or 0.5 mg/kg per day to 37 male and female volunteers for 14 days. In 24 participants 8-and 24-hr measurements of thyroidal 123I uptake (RAIU) were performed before exposure, on exposure days 2 and 14, and 15 days postexposure. Results from the study indicated a true no-effect level of perchlorate of 5.2 or 6.4 µg/kg/day for RAIU. Considering that a 70 kg adult drinks 2 L of water per day, this dose would be ingested if the drinking water contained 182-224 µg/L. In addition, the dose of 0.5 mg/kg/day taken for 14 days did not produce changes in circulating levels of T4 or TSH, suggesting that short-term consumption of perchlorate levels of 17.5 mg/L in drinking water would not affect circulating levels of THs. The authors suggested that this failure of perchlorate to influence circulating levels of TH resulted from the storage capacity of the normal adult thyroid gland, which contains unreleased stored hormones lasting for several months. However, as pointed out by Zoeller (2003), the case may be different for a late gestation fetus or neonate, where the estimated intrathyroidal amount of hormone stored is less than that required for 1 day (Van den Hove et al. 1999; Vulsma et al. 1989). Thus, the concentration of perchlorate sufficient to reduce thyroidal iodine uptake in a fetus or neonate may be sufficient to produce a significant decrement in circulating levels of TH. The fetal thyroid gland obtains iodide for its own TH synthesis from the maternal circulation through the placenta. Placental transfer of perchlorate has been reported in guinea pig (Postel 1957). In human, whether perchlorate crosses from the mother to the fetus during pregnancy is not known. However, this placental transfer could be biologically plausible because expression of the NIS has been reported in human placenta (Bidart et al. 2000). Moreover, perchlorate may concentrate in milk because the NIS protein is induced in lactating breast tissue by prolactin (Tazebay et al. 2000). Perchlorate might decrease iodide uptake into milk, thus reducing the sole source of iodine to the infant. Differently from adults, who most likely can recover from transient hypothyroidism without permanent health consequences, a short period of TH insufficiency may produce permanent neurologic deficits in children (Van Vliet 1999). The study of no-effect level (Greer et al. 2002) was conducted in healthy adults with normal iodine intake, and it is debatable whether 14 days is sufficient time to illustrate perchlorate effect on humans. This no-effect level most likely would be lower in populations with genetic defects causing CH and in populations with lower iodine uptake. The Third National Health and Nutrition Examination Survey (NHANES III), conducted during 1988-1994, found that the percentages of males and females with urinary iodine concentrations < 5 µg/dL were substantially higher in every age category than in the 1971-1974 survey (Hollowell et al. 1998). In pregnant women, these percentages were 6.9% in NHANES III and 1.0% in NHANES I (Hollowell et al. 1998). The overall decline in the last few decades raises concern that a fairly large number of people in the United States may lack adequate iodine intake. Conclusions Exposure to perchlorate, which inhibits iodine uptake, has the biologic potential to cause hypothyroidism and, in pregnant women, severely damage the fetus and the newborn. NHANES III data suggest that 4.3% of the U.S. population may be subclinically hypothyroid (Hollowell et al. 2002). CH affects about 1 in 3,000 to 1 in 4,000 infants and in about 15% of cases may result from a defect of thyroid hormonogenesis, mostly inherited in an autosomal recessive fashion (Vulsma and de Vijlder 2000). Such defects may result from abnormalities in several steps involved in TH synthesis. Our literature review identified possible homozygous or compound heterozygous mutations of genes involved in thyroid iodine synthesis that cause hypothyroidism that could be used to define a potential susceptible population to perchlorate exposure. In a Mendelian fashion, the number of carriers of heterozygous mutated gene causing CH would be higher than the number of the reported CH cases. Given the logical connection between perchlorate, diminished iodine uptake, hypothyroidism, and thyroid-related health effects, people exhibiting heterozygous or homozygous genetic mutations in genes involved in the TH synthesis, especially in a milieu of low iodine uptake, can reasonably be expected to be more susceptible than people who show no genetic variability to the effects of perchlorate. Several studies based on T4 and TSH screening data in infants born to mothers in areas with different perchlorate exposure mostly have found no increase in hypothyroidism incidence. However, these studies lacked estimates of individual perchlorate exposure, as well as estimates of individual iodine uptake. The only study that included iodine values showed no significant association between perchlorate and hypothyroidism. However, it showed high urinary iodide, suggesting the high iodine uptake could easily have upset the inhibition factor of the perchlorate. We conclude that future epidemiologic and population-based studies as well as no-effect studies concerning the link between human disease and environmental perchlorate exposure should consider among their variables the genetic makeup of the participants, actual perchlorate exposure levels, and individual iodine uptake and excretion levels. References Abramowicz MJ, Targovnik H, Varela V, Cochaud P, Krawiec L, Pisarev MA, et al. 1992. Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter. J Clin Invest 90: 1200-1204. Adato A, Raskin L, Petit C, Bonne-Tamir B. 2000. Deafness heterogeneity in a Druze isolate from the Middle East: novel OTOF and PDS mutations, low prevalence of GJB2 35delG mutation and indication for a new DFNB locus. Eur J Hum Genet 8:437-442. Ambrugger P, Stoeva I, Biebermann H, Torresani T, Leitner C, Gruters A. 2001. Novel mutations of the thyroid peroxidase gene in patients with permanent congenital hypothyroidism. Eur J Endocrinol 145:19-24. Anbar M, Guttmann S, Lweitus Z. 1959. The mode of action of perchlorate ions on the iodine uptake of the thyroid gland. Int J Appl Radiat Isot 7:87-96. Bakker B, Bikker H, Hennekam RC, Lommen EJ, Schipper MG, Vulsma T, et al. 2001. Maternal isodisomy for chromosome 2p causing severe congenital hypothyroidism. J Clin Endocrinol Metab 86:1164-1168. Bakker B, Bikker H, Vulsma T, de Randamie JS, Wiedijk BM, de Vijlder JJM. 2000. Two decades of screening for congenital hypothyroidism in the Netherlands: TPO gene mutations in total iodide organification defects (an update). J Clin Endocrinol Metab 85:3708-3712. Bidart JM, Lacroix L, Evain-Brion D, Caillou B, Lazar V, Frydman R, et al. 2000. Expression of Na+/I- symporter and Pendred syndrome genes in trophoblast cells. J Clin Endocrinol Metab 85:4367-4372. Bikker H, Baas F, de Vijlder JJM. 1997. Molecular analysis of mutated thyroid peroxidase detected in patients with total iodide organification defects. J Clin Endocrinol Metab 82:649-653. Bikker H, Den Hartog MT, Baas F, Gons MH, Vulsma T, de Vijlder JJM. 1994. A 20 base pair duplication in the human thyroid peroxidase gene results in a total iodide organification defect and congenital hypothyroidism. J Clin Endocrinol Metab 79:248-252. Bikker H, Vulsma T, Baas F, de Vijlder JJM. 1995. Identification of five novel inactivating mutation in the human thyroid peroxidase gene by denaturing gradient gel electrophoresis. Hum Mutat 6:9-16. Blons H, Feldmann D, Duval V, Messaz O, Denoyelle F, Loundon N, et al. 2004. Screening of SLC26A4 (PDS) gene in Pendred's syndrome: a large spectrum of mutations in France and phenotypic heterogeneity. Clin Genet 66: 333-340. Bogazzi F, Raggi F, Ultimieri F, Campomori A, Cosci C, Berrettini S, et al. 2000. A novel mutation in the pendrin gene associated with Pendred's syndrome. Clin Endocrinol 52:279-285. Bogazzi F, Russo D, Raggi F, Ultimieri F, Berrettini S, Forli F, et al. 2004. Mutations in the SLC26A4 (pendrin) gene in patients with sensorineural deafness and enlarged vestibular aqueduct. J Endocrinol Invest 27:430-435. Brechner R, Parkhurst G, Humble W, Brown M, Herman W. 2000. Ammonium perchlorate contamination of Colorado River drinking water is associated with abnormal thyroid function in newborns in Arizona. J Occup Environ Med 42: 777-782. Campbell C, Cucci RA, Prasad S, Green GE, Edeal JB, Galer CE, et al. 2001. Pendred syndrome, DFNB4, and PDS/SLC26A4: identification of eight novel mutations and possible genotype-phenotype correlations. Hum Mutat 17: 403-411. Coucke PJ, Van Hauwe P, Everett LA, Demirhan O, Kabakkaya Y, Dietrich NL, et al. 1999. Identification of two different mutations in the PDS gene in an inbred family with Pendred syndrome. J Med Genet 36: 475-477. Coyle B, Coffey R, Armour JA, Gausden E, Hochberg Z, Grossman A, et al. 1996. Pendred syndrome (goitre and sensorineural hearing loss) maps to chromosome 7 in the region containing the nonsyndromic deafness gene DFNB4. Nat Genet 12: 421-423. Coyle B, Reardon W, Herbrick JA, Tsui LC, Gausden E, Lee J, et al. 1998. Molecular analysis of the PDS gene in Pendred syndrome. Hum Mol Genet 7:1105-1112. Crump C, Michaud P, Tellez R, Reyes C, Gonzalez G, Montgomery EL, et al. 2000. Does perchlorate in drinking water affect thyroid function in newborns or school-age children? J Occup Environ Med 42:603-612. Dai G, Levy O, Carrasco N. 1996. Cloning and characterization of the thyroid iodide transporter. Nature 379:458-460. De Deken X, Wang D, Many MC, Costagliola S, Libert F, Vassart G, et al. 2000. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J Biol Chem 275:23227-23233. De la Vieja A, Dohán O, Levy O, Carrasco N. 2000. Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiol Rev 80:1083-1095. Dohán O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, et al. 2003. The sodium/iodide symporter (NIS): characterization, regulation and medical significance. Endocr Rev 24:48-77. Dupuy C, Ohayon R, Valent A, Noel-Hudson MS, Deme D, Virion A. 1999. Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs. J Biol Chem 274:37265-37269. Eichler O, Hackenthal E. 1962. [Secretion and metabolism of perchlorate measured with 36ClO4.] Naunyn Schmiedebergs Arch Exp Pathol Pharmakol 243: 554-565. Eskandari S, Loo DD, Dai G, Levy O, Wright EM, Carrasco N. 1997. Thyroid Na+/I symporter. Mechanism, stoichiometry, and specificity. J Biol Chem 272:27230-27238. Everett LA, Glaser B, Beck JC, Idol JR, Buchs A, Heyman M, et al. 1997. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS). Nat Genet 17:411-422. Fraser GR. 1965. Association of congenital deafness with goiter (Pendred's syndrome). Ann Hum Genet 28:201-249. Fugazzola L, Mannavola D, Cerutti N, Maghnie M, Pagella F, Bianchi P, et al. 2000. Molecular analysis of the Pendred's syndrome gene and magnetic resonance imaging studies of the inner ear are essential for the diagnosis of true Pendred's syndrome. J Clin Endocrinol Metab 85:2469-2475. Fujiwara H, Tatsumi K, Miki K, Harada T, Miyai K, Taki S, et al. 1997. Congenital hypothyroidism caused by a mutation in the Na+/I- symporter. Nature Gen 16: 124-125. Fujiwara H, Tatsumi K, Miki K, Harada T, Okada S, Nose O, et al. 1998. Recurrent T354P mutation of the Na+/I symporter in patients with iodide transport defect. J Clin Endocrinol Metab 83:2940-2943. Fujiwara H, Tatsumi K, Tanaka S, Kimura M, Nose O, Amino N. 2000. A novel V59E missense mutation in the sodium iodide symporter gene in a family with iodide transport defect. Thyroid 10:471-474. Greer MA, Goodman G, Pleus RC, Greer SE. 2002. Health effects assessment for environmental perchlorate contamination: the dose-response for inhibition of thyroidal radioiodine uptake in humans. Environ Health Perspect 110: 927-937. Greer MA, Stott AK, Milne KA. 1966. Effects of thiocyanate, perchlorate and other anions on thyroidal iodine metabolism. Endocrinology 79:237-247. Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, et al. 2002. Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 87:489-499. Hollowell JG, Staehling NW, Hannon WH, Flanders DW, Gunter EW, Maberly GF, et al. 1998. Iodine nutrition in the United States. Trends and public health implications: iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971-1974 and 1988-1994). J Clin Endocrinol Metab 83:3401-3408. Johnsen T, Videbaek H, Olsen KP. 1989. CT-scanning of the cochlea in Pendred's syndrome. Clin Otolaryngol 14:389-393. Kelada SN, Eaton DL, Wang SS, Rothman NR, Khoury MJ. 2003. The role of genetic polymorphisms in environmental health. Environ Health Perspect 111: 1055-1064. Kirk AB, Smith EE, Tian K, Anderson TA, Dasgupta PK. 2003. Perchlorate in milk. Environ Sci Technol 37: 4979-4981. Kopp P, Arseven OK, Sabacan L, Kotlar T, Dupuis J, Cavaliere H, et al. 1999. A novel mutation in the sodium/iodide symporter gene in the largest family with iodide transport defect. J Clin Endocrinol Metab 84:336-341. Kosugi S, Bhayana S, Dean HJ. 1999. A novel mutation in the sodium/iodide symporter gene in the largest family with iodide transport defect. J Clin Endocrinol Metab 84:3248-3253. Kosugi S, Inoue S, Matsuda A, Jhiang SM. 1998b. Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients. J Clin Endocrinol Metab 83: 3373-3376. Kosugi S, Okamoto H, Tamada A, Sanchez-Franco F. 2002. A novel peculiar mutation in the sodium/iodide symporter gene in Spanish siblings with iodide transport defect. J Clin Endocrinol Metab 87:3830-3836. Kosugi S, Sato Y, Matsuda A, Ohyama Y, Fujieda K, Inomata H, et al. 1998a. High prevalence of T354P sodium/iodide symporter gene in Spanish siblings with iodide transport defect. J Clin Endocrinol Metab 83:4123-4129. Kotani T, Umeki K, Kawano J, Suganuma T, Hishinuma A, Ieiri T, et al. 2003. Partial iodide organification defect caused by a novel mutation of the thyroid peroxidase gene in three siblings. Clin Endocrinol 59: 198-206. Kotani T, Umeki K, Yamamoto I, Ohtaki S, Adachi M, Tachibana K. 2001. Iodide organification defects resulting from cosegregation of mutated and null thyroid peroxidase alleles. Mol Cell Endocrinol 182:61-68. Lamm SH, Doemland M. 1999. Has perchlorate in drinking water increased the rate of congenital hypothyroidism? J Occup Environ Med 41:409-411. Li FX, Byrd DM, Deyhle GM, Sesser DE, Skeels MR, Katkowsky SR, et al. 2000. Neonatal thyroid stimulating hormone level and perchlorate in drinking water. Teratology 62:429-431. Li XC, Everett LA, Lalwani AK, Desmukh D, Friedman TB, Green ED, et al. 1998. A mutation in PDS causes non-syndromic recessive deafness. Nat Genet 18:215-217. Li Z, Li FX, Byrd D, Deyhle GM, Sesser DE, Skeels MR, et al. 2000. Neonatal thyroxine level and perchlorate in drinking water. J Occup Environ Med 42: 200-205. Lopez-Bigas N, Melchionda S, de Cid R, Grifa A, Zelante L, Govea N, et al. 2002. Identification of five new mutations of PDS/SLC26A4 in Mediterranean families with hearing impairment. Hum Mutat 20:77-78. Mangklabruks A, Billerbeck AE, Wajchenberg B, Knobel M, Cox NJ, DeGroot LJ, et al. 1991. Genetic linkage studies of thyroid peroxidase (TPO) gene in families with TPO deficiency. J Clin Endocrinol Metab 72:471-476. Matsuda A, Kosugi S. 1997. A homozygous missense mutation of the sodium/iodide symporter gene causing iodide transport defect. J Clin Endocrinol Metab 82 3966-3971. Moreno JC, Bikker H, Kempers MJ, van Trotsenburg AS, Baas F, de Vijlder JJ, et al. 2002. Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. N Engl J Med 347:95-102. Motzer WE. 2001. Perchlorate: problems, detection, and solutions. Environ Forensics 2:301-311. Namba A, Abe S, Shinkawa H, Kimberling WJ, Usami SI. 2001. Genetic features of hearing loss associated with ear anomalies: PDS and EYA1 mutation analysis. J Hum Genet 46: 518-521. Nascimento AC, Guedes DR, Santos CS, Knobel M, Rubio IG, Medeiros-Neto G. 2003. Thyroperoxidase gene mutations in congenital goitrous hypothyroidism with total and partial iodide organification defect. Thyroid 13: 1145-1151. Nilsson LR, Borgfors N, Gamstorp I, Holst HE, Liden G. 1964. Nonendemic goitre and deafness. Acta Paediatr 53:117-131. Niu DM, Hwang B, Chu YK, Liao CJ, Wang PL, Lin CY. 2002. High prevalence of a novel mutation (2268 insT) of the thyroid peroxidase gene in Taiwanese patients with total iodide organification defect and evidence for a founder effect. J Clin Endocrinol Metab 87:4208-4212. Pannain S, Weiss RE, Jackson CE, Dian D, Beck JC, Sheffield VC, et al. 1999. Two different mutations in the thyroid peroxidase gene of a large inbred Amish kindred: power and limits of homozygosity mapping. J Clin Endocrinol Metab 84:1061-1071. Park HJ, Shaukat S, Liu XZ, Hahn SH, Naz S, Ghosh M, et al. 2003. Origins and frequencies of SLC26A4 (PDS) mutations in east and south Asians: global implications for the epidemiology of deafness. J Med Genet 40:242-248. Pohlenz J, Medeiros-Neto G, Gross JL, Silveira SP, Knobel M, Refetoff, S. 1997. Hypothyroidism in a Brazilian kindred due to iodide trapping defect caused by a homozygous mutation in the sodium/iodide symporter gene. Biochem Biophys Res Commun 240:488-491. Pohlenz J, Rosenthal IM, Weiss RE, Jhiang SM, Burant C, Refetoff S. 1998. Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site. J Clin Invest 101:1028-1035. Postel S. 1957. Placental transfer of perchlorate and triiodothyronine in the guinea pig. Endocrinology 60:53-66. Prasad S, Kolln KA, Cucci RA, Trembath RC, Van Camp G, Smith RJ. 2004. Pendred syndrome and DFNB4-mutation screening of SLC26A4 by denaturing high-performance liquid chromatography and the identification of eleven novel mutations. Am J Med Genet 124A:1-9. Reardon W, Coffey R, Chowdhury T, Grossman A, Jan H, Britton K, et al. 1999. Prevalence, age of onset, and natural history of thyroid disease in Pendred syndrome. J Med Genet 36:595-598. Reardon W, O'Mahoney CF, Trembath R, Jan H, Phelps PD. 2000. Enlarged vestibular aqueduct: a radiological marker of Pendred syndrome, and mutation of the PDS gene. Q J Med 93:99-104. Rivolta CM, Esperante SA, Gruneiro-Papendieck L, Chiesa A, Moya CM, Domene S, et al. 2003. Five novel inactivating mutations in the thyroid peroxidase gene responsible for congenital goiter and iodide organification defect. Hum Mutat 22:259. Santos CL, Bikker H, Rego KGM, Nascimento AC, Tambascia M, De Vijlder JJM, et al. 1999. A novel mutation in the TPO gene in goitrous hyperthyroid patients with iodide organification defect. Clin Endocrinol 51:165-172. Schwartz J. 2001. Gestational Exposure to Perchlorate Is Associated with Measures of Decreased Thyroid Function in a Population of California Neonates [Master's thesis]. Berkeley, CA:University of California Berkeley. Scott DA, Wang R, Kreman TM. 2000. Functional differences of the PDS gene product are associated with phenotypic variation in patients with Pendred syndrome and non-syndromic hearing loss (DFNB4). Hum Mol Genet 9: 1709-1715. Sheffield VC, Kraiem Z, Beck JC, Nishimura D, Stone EM, Salameh M, et al. 1996. Pendred syndrome maps to chromosome 7q21-34 and is caused by an intrinsic defect in thyroid iodine organification. Nat Genet 12:424-426. Smith PN, Theodorakis CW, Anderson TA, Kendall RJ. 2001. Preliminary assessment of perchlorate in ecological receptors at the Longhorn Army Ammunition Plant (LHAAP), Karnack, Texas. Ecotoxicology 10:305-313. Soldin OP, Braverman LE, Lamm SH. 2001. Perchlorate clinical pharmacology and human health: a review. Ther Drug Monit 23:316-331. Stanbury JB, Wyngaarden JB. 1952. Effect of perchlorate on the human thyroid gland. Metabolism 1: 533-539. Tazebay UH, Wapnir IL, Levy O, Dohan O, Zuckier LS, Zhao QH, et al. 2000. The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nat Med 6:871-878. Tekin M, Akcayoz D, Comak E, Bogoclu G, Duman T, Fitoz S, et al. 2003. Screening the SLC26A4 gene in probands with deafness and goiter (Pendred syndrome) ascertained from a large group of students of the schools for the deaf in Turkey. Clin Genet 64:371-374. Tonacchera M, Agretti P, De Marco G, Elisei R, Perri A, Ambrogini E, et al. 2003. Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein. Clin Endocrinol 59:500-506. Tonacchera M, Pinchera A, Dimida A, Ferrarini E, Agretti P, Vitti P, et al. 2004. Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter. Thyroid 12:1012-1019. Tsukamoto K, Suzuki H, Harada D, Namba A, Abe S, Usami S. 2003. Distribution and frequencies of PDS (SLC26A4) mutations in Pendred syndrome and nonsyndromic hearing loss associated with enlarged vestibular aqueduct: a unique spectrum of mutations in Japanese. Eur J Hum Genet 11:916-922. Umeki K, Kotani T, Kawano J, Suganuma T, Yamamoto I, Aratake Y, et al. 2002. Two novel missense mutations in the thyroid peroxidase gene, R665W and G771R, result in a localization defect and cause congenital hypothyroidism. Eur J Endocrinol 146:491-498. Umeki K, Yamamoto I, Yukizane S, Kotani T. 2004. Congenital hypothyroidism caused by a unique thyroid peroxidase allele containing two mutations, C1708T and C2737T. J Pediatr Endocrinol Metab 17:231-234. Usami S, Abe S, Weston MD, Shinkawa H, Van Camp G, Kimberling WJ. 1999. Non-syndromic hearing loss associated with enlarged vestibular aqueduct is caused by PDS mutations. Hum Genet 104:188-192. van den Hove MF, Beckers C, Devlieger H, de Zegher F, De Nayer P. 1999. Hormone synthesis and storage in the thyroid of human preterm and term newborns: effect of thyroxine treatment. Biochimie 81:563-570. Van Hauwe P, Everett LA, Coucke P, Scott DA, Kraft ML, Ris-Stalpers C, et al. 1998. Two frequent missense mutations in Pendred syndrome. Hum Mol Genet 7: 1099-1104. van Vliet G. 1999. Neonatal hypothyroidism: treatment and outcome. Thyroid 9:79-84. Vulsma T, de Vijlder JIM. 2000. Thyroid disease in newborns, infants and children. In: Oxford Textbook of Endocrinology and Diabetes (Wass JAH Shalet SM, eds). Oxford, UK:Oxford University Press, 532-544. Vulsma T, Gons MH, de Vijlder JJ. 1989. Maternal-fetal transfer of thyroxine in congenital hypothyroidism due to a total organification defect or thyroid agenesis. N Engl J Med 321:13-16. Wolff J. 1998. Perchlorate and the thyroid gland. Pharmacol Rev 50:89-105. Wu JY, Shu SG, Yang CF, Yang CF, Lee CC, Tsai FJ, et al. 2002. Mutation analysis of thyroid peroxidase gene in Chinese patients with total iodide organification defect: identification of five novel mutations. J Endocrinol 172:627-635. Wyngaarden JB, Stanbury JB, Rapp B. 1953. The effects of iodide, perchlorate, thiocyanate and nitrate administration upon the iodide concentrating mechanism of the rat thyroid. Endocrinology 52:568-574. Yong AM, Goh SS, Zhao Y, Eng PH, Koh LK, Khoo DH. 2001. Two Chinese families with Pendred's syndrome: radiological imaging of the ear and molecular analysis of the pendrin gene. J Clin Endocrinol Metab 86: 3907-3911. Yoshida A, Taniguchi S, Hisatome I, Royaux IE, Green ED, Kohn LD, et al. 2002. Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells. J Clin Endocrinol Metab 87:3356-3361. Zoeller RT. 2003. Challenges confronting risk analysis of potential thyroid toxicants. Risk Anal 23: 143-162. Zoeller RT, Dowling AL, Herzig CT, Iannacone EA, Gauger KJ, Bansal R. 2002. Thyroid hormone, brain development, and the environment. Environ Health Perspect 110(suppl 3): 355-361. Republished from Environmental Health Perspectives Volume 113, Number 11, November 2005 © 2004-2005 by foodconsumer.org unless otherwise specified Agri. & Environ. © 2004-2005 foodconsumer.org™all rights reserved hosted by marsgerm.com ***************************************************************** 34 Nevada: Changes Being Planned For Yucca Mountain, Vol. 3, No. 1 October 31, 2005 Nevada's Online State News Journal Designed To Increase Safety At The Site Spent Nuclear Fuel Casks Shipped And Stored; Must Be Approved By NRC And Others Changes in the handling of high level nuclear waste were announced by the Department of Energy (DOE) recently. The changes must still be approved by various agencies such as the Nuclear Regulatory Commission. Interestingly, the new plan is one of the reasons that so many feel the Yucca Mountain Repository is already out of date. The new plan, touted as an "improvement in safety and reliability of operations at Yucca" calls for the spent fuel to be stored in the same casks that will be used for transportation from nuclear energy production plants across the country. In previous plans the waste would have been transferred from the transportation cask to a storage cask. According to a DOE fact sheet "This design will be simpler and more straightforward, reduce programmatic risk, and take complexity out of the NRC licensing process." In a speech to Congress recently Utah Senator Bennett, (D) said that if the casks that have been designed are safe enough for shipment and storage, why bother moving them? In the same discussion Bennett pointed out that there is already more high level nuclear waste available for storage than the Yucca Mountain Repository has space for. The new plan was offered by DOE's Office of Civilian Radioactive Waste Management (OCRWM) and is called a "Clean" program for waste storage. According to Paul Golan, OCRWM's Acting Director, "Our new path forward will provide clear direction to improve safety and reliability as well as reduce programmatic risk." Nevada Congresswoman Shelley Berkley (D) scoffs at the image of "clean." "Calling plans to dump radioactive garbage in Nevada 'clean' is an insult to the intelligence of families in the Silver State." Berkley goes on to say, the plan "ignores the fact that nuclear waste is one of the deadliest substances on earth." The change in design letter was sent to Bechtel SAIC, the Yucca Mountain Prime Contractor. According to a DOE press release the new plan will be submitted to the Secretary of Energy's Acquisition Advisory Board for review. Nuclear energy plants are located throughout the country and the high level nuclear waste that comes from the generation of energy at the plants is scheduled to be sent to Yucca Mountain north of Las Vegas. Berkley says that right now, "The DOE is desperate to show that Yucca Mountain is moving ahead, despite the fact that it's already years behind schedule and poses an enormous threat to public safety and the environment." All types of plans for the transportation of the waste have been discussed over the years. One plan includes building a new railroad from Battle Mountain south to Yucca. That plan according to the latest information available seems to have been abandoned. However, a railroad is planned to run from Caliente along the southern Nevada border with Utah, around the Southern Nevada Test Site to Yucca. That rail line would be slightly more than 300 miles in length. Other transportation methods include regular rail and truck routes. Since the nuclear energy plants are located where the most energy is needed, the transportation routes look like they will travel through very high-density population centers. Congresswoman Berkley says, "Regardless of how they repackage this waste, at the end of the day, it's still going to be dumped in Nevada, and it's still going to threaten the lives of million of Americans living along the transportation routes." Many are confused by this change in plans, including Berkley. "The fact they are still changing the design and have abandoned any timetable for submitting a license for the dump only proves how desperate they've become and how many obstacles remain." Berkley echoes the words of Senator Bennett by declaring, "The only safe solution is to keep nuclear waste at the plants where it was produced and where it can be safely stored." ••• ***************************************************************** 35 UK: News & Star: Irish demand action at Sellafield Published on 02/11/2005 By Andrea Thompson A GROUP of Irish councillors are calling for an end to nuclear waste dumping at Drigg – and for rapid action to clean up contamination at both the repository and nearby Sellafield. Members of the newly-formed All Ireland Nuclear Free Local Authorities Forum met to discuss nuclear activity across the Irish Sea. They are concerned about the safety of radioactive waste at Drigg because, they say, the site is vulnerable to coastal erosion and rising sea levels caused by global climate change. Coastal erosion may reach the low level waste repository within 500 years, but Irish authorities fear increasing rates of thawing in Polar regions mean Drigg could be flooded far faster – with the Sellafield nuclear plant also at risk. The forum has written to the Environment Agency of England and Wales to voice its concerns, saying that, in future, Drigg should only be a temporary storage facility, and that waste should be moved to a safer site further inland. The forum also believes that the Nuclear Decommissioning Authority should speed up cleaning at Sellafield. Chairman of the forum, Michael O’Dowd, said: “Both Drigg and Sellafield could literally fall into the Irish Sea, and the British government must act now to prevent an environmental disaster in the future. Drigg contains radioactive waste, some of which has a half-life of 245,000 years.†South Dublin councillor Tony McDermott added: “We must assume that the worst will happen and take a precautionary approach to minimise the risks from erosion at these sites. “This means an end to radioactive waste dumping at Drigg and rapid action to clean up contamination at both Drigg and Sellafield.†***************************************************************** 36 Las Vegas SUN: BLM blocking Skull Valley nuclear waste project November 01, 2005 By PAUL FOY ASSOCIATED PRESS SALT LAKE CITY (AP) - A federal Bureau of Land Management official said Tuesday he was refusing to give the agency's approval for a rail spur for a nuclear waste stockyard in Utah's west desert. The utilities backing the project say they might resort to trucking the waste on a state highway, but the BLM official in charge said his agency had the power to veto that, too. "We're not able to bring anything to conclusion on their behalf," Glenn A. Carpenter, field manager for the bureau's Salt Lake district, told The Associated Press. The BLM's refusal is one of a series of bureaucratic obstacles erected by the state's congressional delegation to stop Private Fuel Storage, a consortium of out-of-state utilities that won approval from the Nuclear Regulatory Commission in September to build the way-station for nuclear waste. The Skull Valley band of Goshute Indians signed a lucrative contract to take the radioactive waste from other states' nuclear-powered utilities. The utilities call it a temporary solution pending a resolution of the troubled federal project at Nevada's Yucca Mountain, but Utah politicians fear it will become a permanent repository. Sen. Orrin Hatch, R-Utah, said the Bureau of Land Management's refusal to cooperate is a sign that the Bush administration is "on our side." In a statement issued Tuesday, Hatch said the agency has "jammed" the license authorized but not yet issued by the Nuclear Regulatory Commission. The stockpiling of 44,000 tons of spent nuclear fuel would take place about 45 miles southwest of Salt Lake City. "This is one of many administrative and legal hurdles we are raising that PFS has to clear for Skull Valley to ever become a reality," Hatch said. In an interview, Carpenter said the BLM cannot make a decision to authorize the construction of a Skull Valley rail line over government land because of restrictions Rep. Jim Hansen, R-Utah, wrote into a 2000 defense appropriations bill. Hansen's provision blocked the bureau from changing a land-use plan to grant a right of way across government land for the rail line. The Bureau of Land Management can't act until the Pentagon studies how proposed wilderness areas for Utah's west desert might affect operations at the Utah Test and Training Range. The Pentagon is nowhere near starting the study. Private Fuel Storage Chairman and Chief Executive Officer John Parkyn has said he might be able to get around the problem by shipping the waste by truck, but Carpenter said that was no certain bet. Two-lane State Route 196 is not wide enough to accommodate trucks hauling the steel casks holding the nuclear waste, he said, and the Bureau of Land Management would have to grant a new right of way for any widening project. The state isn't likely to back road reconstruction for a project it's vigorously opposing. In the end, the Hasting's Cutoff, a route used by the ill-fated Donner Party in 1846, could defeat Private Fuel Storage's proposal. Carpenter said the reworked tracks of Hasting's Cutoff and subsequent Lincoln Highway are historic Skull Valley assets that could be damaged by a rail spur crossing them to Indian reservation. Even if the bureau had authority to change its land-use plan for Skull Valley, Carpenter hinted it would be hesitant to endanger "an old route that remains traveled to this day, worn in the landscape by subsequent travel." All contents copyright 2005 Las Vegas SUN, Inc. ***************************************************************** 37 CH2M HILL Mound, Inc.: Announces Building Demolition Complete at Miamisburg Mound Project Site MIAMISBURG, Ohio, Nov. 1 /PRNewswire/ -- The U.S. Department of Energy (DOE) and cleanup contractor CH2M HILL Mound, Inc. announced today that demolition of more than 566,000 square-feet of nuclear, radiological and commercial facilities at the Miamisburg Mound Project site is complete. In December 2002, DOE awarded CH2M HILL a $314-million, performance-based contract to accelerate the safe closure of the nuclear facilities at the former Mound Plant in Miamisburg, Ohio. DOE established the 306-acre site in 1946 to conduct nuclear research, design development, manufacturing, and testing of nuclear weapons and spacecraft components. CH2M HILL's accelerated baseline targets completion of the project less than two years from previous contractors' estimates. To achieve cleanup and closure of the site, CH2M HILL Mound, Inc. is providing facility demolition, environmental restoration and waste management services, including: * Demolition of 64 facilities and transfer of nine facilities to the Miamisburg Mound Community Improvement Corporation (MMCIC) for industrial reuse * Removal of all above ground utility structures and components * Investigation, clean up, closure and documentation of 73 soil contaminated sites * Storage, characterization, processing, packaging and shipment of materials from the cleanup process Since the contract's inception nearly three years ago, CH2M HILL Mound, Inc. has focused on safe, accelerated delivery of the project. During demolition of 64 buildings, the project did not experience a lost work day case or recordable case by the Occupational Safety and Health Administration (OSHA). "I am very pleased that through this closure contract, we have been able to safely meet our commitments to our regulators and stakeholders," said Jim Rispoli, Assistant Secretary of Energy for Environmental Management. "The safe completion of the demolition work is attributable to the workforce at Mound," said John Lehew, president and site manager. Also completed earlier this year were the final shipments of transuranic (TRU) waste and excess nuclear materials from the site. Headquartered in Denver, employee-owned CH2M HILL is a global firm providing engineering, construction, operations, and related technical services to public and private clients. With more than $3 billion in revenue, CH2M HILL is an industry leading program management, construction management for fee, and design firm, as ranked by Engineering-News Record (2005). The firm's work is concentrated in the areas of transportation, water, energy, environment, communications, construction, and industrial facilities. CH2M HILL has more than 15,000 employees in 450 offices worldwide. CONTACT: Lynette Bennett CH2M HILL Mound, Inc. (937) 673-4574 Lynette.Bennett@ch2m.com Copyright © 1996-2003 PR Newswire Association LLC. All Rights ***************************************************************** NOTE: In accordance with Title 17 U.S.C. section 107 this material is distributed without profit or payment to those who have expressed a prior interest in receiving this information for non-profit research and educational purposes only. For more information go to: *****************************************************************